氯乙酸水解合成羟基乙酸的合成条件改进  

Synthesis of Hydroxyacetic Acid Produced by Hydrolysis

作　　者：邰燕芳[1,2] 吴景梅[1] 董雄辎[2] 

机构地区：[1]蚌埠学院化学与材料实验室,安徽蚌埠233000 [2]合肥工业大学化工学院,安徽合肥230009

出　　处：《云南民族大学学报（自然科学版）》2012年第6期412-414,共3页Journal of Yunnan Minzu University:Natural Sciences Edition

摘　　要：研究了氯乙酸水解合成羟基乙酸的各种影响因素,包括氯乙酸和氢氧化钠的物质的量比,反应温度,反应时间以及氢氧化钠的质量分数.得出理想的反应条件为:氯乙酸和氢氧化钠的物质的量比为1.15∶1,反应温度为105℃,反应时间为10 h,氢氧化钠的质量分数为40%,此反应条件下羟基乙酸的产率大于93%.且该方法工艺简单,易操作,对环境污染小.The influencing factors on synthesizing hydroxyacetic acid from chloroactic acid were studied, including the reaction temperature, the reaction time, the property of NaOH and the tool ratio of NaOH and chloroactic acid. The optimum reaction conditions are as follows： n（chloroactic acid）： n （NaOH） = 1.15：1, the reaction temperature was 105 ℃ , the reaction time was 10 h, and the w（NaOH） was 40%. The yield of hydroxyacetic acid was over 93%. The method is simple and less harmful to the environment.

关 键 词：氯乙酸 羟基乙酸 合成 

分 类 号：O621.3[理学—有机化学]