金黄散联合地塞米松预防阿霉素所致静脉炎的临床观察  

Clinical observation of preventing adriamycin-induced infusion phlebitis with Jin Huang San and dexamethasone

作　　者：孙敏[1] 朱国亚[1] 曹庆荣[1] 

机构地区：[1]安徽省立医院,合肥230001

出　　处：《安徽卫生职业技术学院学报》2012年第5期54-55,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:观察金黄散联合地塞米松预防阿霉素所致的静脉炎的疗效。方法:共收治乳腺癌患者90例,分为三组,每组30例,三组均接受含阿霉素的化疗方案。A组在推注阿霉素前、后给予地塞米松2.5mg静脉点滴;B组在推注阿霉素前将调好的金黄散在注射点沿静脉向心走向湿敷;C组在推注阿霉素前按照A组患者方法静滴地塞米松,同时按B组方法湿敷金黄散。结果:三组的静脉炎发生严重程度以C组最轻,A组最重,差异有统计学意义(P<0.05);三组的疼痛程度C组最轻,A组最重,差异有统计学意义(P<0.05)。结论:金黄散湿敷联合地塞米松可以降低阿霉素所致静脉炎的发生率,减轻发生程度。Objective：To evaluate the effect of Jin Huang San and dexamethasone in treating of adriamycin-in- duced infusion phlebitis.Methods：Ninety patients with breast cancer were divided into three groups,which were treated with adriamycin. The group A （30 cases） were given the intravenous dexamethasone before and after bolus injection of adriamycin,the group B （30 cases） was used with Jin Huang San wet compressing before infusion along the vein,the group C （30 cases） was treated combining Jin Huang San and dexamethasone. Results ： By comparison on the infusion phlebitis and pain in the three groups,the group C was superior to that of the others,the difference was statistically sig- nificant （P〈0.05）.Conclusion：h has greater benefit to use Jin Huang San and intravenous dexamethasone to reduce the incidence and level of adriamycin-induced infusion phlebitis.

关 键 词：金黄散 地塞米松 化疗性静脉炎 预防 

分 类 号：R543.6[医药卫生—心血管疾病]