不同肺复张方法在ARDS治疗中的应用研究  

Effects comparison of three recruitment maneuvers for acute respiratory distress syndrome

作　　者：许军[1] 曹赋韬[1] 陆肖娴[1] 

机构地区：[1]南京医科大学附属无锡市第二人民医院,江苏无锡214002

出　　处：《海南医学院学报》2012年第11期1596-1598,共3页Journal of Hainan Medical University

基　　金：中国高校医学期刊临床专项资金项目(112210396)~~

摘　　要：目的:探讨三种不同的肺复张方法(RM)应用于治疗急性呼吸窘迫综合征(ARDS)患者的效果。方法:将63例ARDS患者随机分为A、B、C三组,每组21例,分别应用控制性肺膨胀、呼吸末正压递增法、压力控制法三种肺复张方法治疗,观察记录RM治疗前后患者氧和指数(PO2)、心率(HR)、中心静脉压(CVP)、平均动脉压(MAP)、动脉血氧分压(PaO2)、血氧饱和度(SpO2)指标的变化,并统计分析。结果:C组患者PaO2、PO2、SpO2水平在5min、10min显著高于其它两组(P<0.05);RM后三组患者短时间内心率均增快,CVP下降,MAP上升,A组变化幅度最大(P<0.05),25min后三组数据之间无显著差异(P>0.05)。结论:三种方法综合比较发现,压力控制法应用于ARDS患者的治疗更具有优势。Objective. To compare effects of three recruitment maneuvers （RM） for acute respira tory distress syndrome （ARDS）. Methods=A total of 63 ARDS patients were randomly divided into group A （21 cases）, group B （21 cases） and group C （21 cases）, which were treated by three RM including sus- tained inflation （SI）, increase progressively PEEP （IP） and pressure control ventilation（PCV）, respec- tively. Heart rate, mean arterial blood pressure （MAP）, central venous pressure （CVP） were recorded before and after RM and analyzed. Results. Level of PaO2 ,PO2 and SpO2 of group C were significant higher than that of the other two groups （P〈0.05）. After RM, MAP and heart rate were increased in short time, O. 05） but CVP was However, 25 PCV method shows decreased, min later, advantages changes of the CVP a over the o were more obviously than the other of three groups were similar （P〉0. methods in ARDS treatment. two groups （P~ 05）. Conclusion：

关 键 词：急性呼吸窘迫综合征 控制性肺膨胀 呼吸末正压递增法 压力控制法 

分 类 号：R563.8[医药卫生—呼吸系统]