清肝降脂汤治疗非酒精性脂肪肝的临床疗效研究  

The clinical efficacy of Qinggan Jiangzhi decoction on patients with non-alcoholic fatty liver disease

作　　者：余世敏 胡东辉 张京伟[2] 

机构地区：[1]湖北省中山医院肝病科,武汉430000 [2]武汉大学中南医院肿瘤外科,武汉430000

出　　处：《重庆医学》2012年第31期3255-3256,3259,共3页Chongqing medicine

基　　金：湖北省自然科学基金资助项目(2009CDB222)

摘　　要：目的观察中西医结合治疗非酒精性脂肪肝(NAFLD)的临床疗效。方法将60例NAFLD患者随机分为治疗组和对照组,各30例,治疗组在西医常规治疗基础上加用自拟清肝降脂汤加减,对照组单纯采用西医常规治疗。治疗12周后评价两组患者治疗效果及肝功能、血脂指标。结果治疗组、对照组的总有效率分别为93.3%、83.3%,治疗组的疗效明显优于对照组,差异有统计学意义(P<0.05);两组治疗后的肝功能及血脂指标均优于治疗前(P<0.05),而治疗组治疗后的肝功能及血脂指标均明显优于对照组(P<0.01)。结论中西医结合治疗NAFLD的疗效显著,且安全性好。Objeetive To observe the clinical efficacy of combined Chinese and Western medicine treatment on non-alcoholic fat- ty liver disease（NAFLD）. Methods 60 patients with NAFLD were equally randomized into treatment group（n= 30） and control group（n= 30）. The two groups were both given Western medicine routine treatment. However, the treatment group was treated with Qinggan Jiangzhi decoction in addition. All patients were treated for a period of treatment, which was 12 weeks. Then we eval- uated the treatment outcome,liver function and blood lipid index of two groups. Results The total effective rate of treatment group and control group was 93.3% and 83.3%, and the difference was significant（P〈0.05）. Liver function and lipid index of two groups after treatment were better than before（P〈0.05）. After treatment, the liver function and lipid indicators of treatment group were much better than those of control group（P〈0.01）. Conclusion The combined treatment of Chinese and Western medicine on NAFLD has a good clinical effect.

关 键 词：非酒精性脂肪肝 中西医结合 清肝降脂汤 

分 类 号：R259[医药卫生—中西医结合]