杜仲颗粒结合常规疗法治疗妊娠期高血压疾病的临床疗效  

Clinical efficacy of combined treatment by eucommia granules and conventional therapy for hypertensive disorder complicating pregnancy

作　　者：彭红梅[1] 李小姝[1] 杨亚培[1] 

机构地区：[1]郑州大学第二附属医院妇产科,450014

出　　处：《重庆医学》2012年第31期3262-3264,共3页Chongqing medicine

基　　金：河南省科技攻关计划资助项目(102300410071)

摘　　要：目的探讨杜仲颗粒结合常规疗法治疗妊娠期高血压疾病(HDCP)的临床疗效。方法将产科保守治疗的小于34周的HDCP患者90例随机分为两组,杜仲颗粒治疗组(A组)60例,常规治疗组(B组)30例,两组患者治疗前及治疗2周后均行血流动力学检测及24h动态血压监测,观察治疗前后两项检查指标的变化及妊娠结局。结果 A组心功能改善总有效率优于B组,差异有统计学意义(P<0.05);24h动态血压监测结果比较,A组白天及夜间收缩压及舒张压均值低于B组,差异有统计学意义(P<0.05);治疗结束后,两组延长孕周的时间,母亲并发症,新生儿出生体质量及Apgar评分,新生儿转儿科比较,差异均有统计学意义(P<0.05)。结论杜仲颗粒结合常规疗法可明显改善HDCP患者母婴结局,为发生在34周之前的HDCP的治疗提供了新的途径。Objective To investigate the effect of eucommia granules and conventional therapy in the treatment of hypertensive disorder complicating pregnancy（HDCP）. Methods A total of 90 cases of HDCP were randomly divided into 2 groups： The eu- commia granules treatment group（group A： 60 cases）and the conventional treatment group（group B： 30 cases）,all the patients un- derwent hemodynamic test and 24 h ambulatory blood pressure monitoring before treatment and 2 weeks later,then we observed in- dex changes of the two checks and pregnancy outcomes. Results （1） With the total effective rate of cardiac function improvement, the group A surpassed group B,the difference was statistically significant（P〈0.05）. （2） The 24 hour ambulatory blood pressure monitoring results： the mean of day and night systolic blood pressure（SBP） and diastolic blood pressure（DBP） of the group A were lower than group B, the difference was statistically significant（P〈0.05）. （3）After the end of treatment, extending the time of ges- rational age, mother complications, birth weight, 1-minute Apgar scores and newborn turn to department of paediatrics in the group A compared with group B, differences were statistically significant（P〈0.05）. Conclusion The combined treatment of eucommia granules and conventional therapy can significantly improve maternal and neonatal outcomes in patients with HDCP, which provides a new way for the therapy in patients with HDCP whose gestational age were less than 34 weeks.

关 键 词：高血压 妊娠性 血流动力学 血压监测 便携式 杜仲 

分 类 号：R714.246[医药卫生—妇产科学]