无偿献血者抗-HCV与ALT检测结果的分析  

Analysis unpaid blood donors Anti-HCV and ALT test results

作　　者：张瑞欣 王洪[2] 王志梅[2] 张红梅[2] 燕锋[2] 李俊霞[2] 徐晓燕[2] 郝彦开[2] 

机构地区：[1]邯郸市邯山区疾病预防控制中心 [2]邯郸市中心血站,河北邯郸056001

出　　处：《中国美容医学》2012年第07X期36-37,共2页Chinese Journal of Aesthetic Medicine

摘　　要：目的:调查分析无偿献血者抗-HCV检测结果与ALT值的关系。方法:对邯郸市2009年3月～2010年2月18～55岁20 847名献血者5项检测结果行Epi dat a3.0双录入,导入SPSS13.0,统计抗-HCV阳性者与健康献血者ALT的几何均数,并进行检验,检验水准α=0.05。结果:抗-HCV阳性者与健康献血ALT值的几何均数分别为20.61U/l和17.28 U/l;α=2.012,P=0.046,P<0.05,差异有统计学意义。抗-HCV阳性127例中有23例ALT>40EU/l,不合格率为18.11%;合格率为81.89%。结论:抗-HCV阳性献血人群ALT水平高于健康献血人群;ELI SA方法对于HCV阳性的检出高于ALT对HCV的检出,ALT作为HCV感染窗口期检测的意义不大。Objective Investigation and analysis of the relationship of unpaid blood donors Anti-HCV testing results and the ALT value. Methods： In March of 2009 - 2010 February in Handan, 18 to 55 years old 20847 donors five test results do Epidata3.0 double entry, import SPSS 13.0 in statistical analysis Anti-HCV positive and healthy blood donors ALT geometric mean, and to t＇-test. Inspection level =0.05. Results：Anti-HCV positive and healthy blood donation ALT value geometric mean were 20.61 U/L and 17.28 U/I; t＇=2.012, P=0.046,P 〈0.05, there have statistical difference between groups. Among Anti-HCV positives 127 case, exist 23 ALT〉40U/L, was 18.11 percent, and 81.89 percent Anti-HCV positives ALT value was qualified. Conclusion：The ALT value of Anti-HCV positives was higher than health donors; ELISA method for HCV positive detection higher than the detection of ALT. ALT detection has little sense for the window period of HCV infection.

关 键 词：献血者 丙氨酸氨基转移酶(ALT) 抗-HCV 

分 类 号：R446.6[医药卫生—诊断学]