我院注射用硫酸头孢噻利干预前后应用分析  

Analysis on utilization of cefoselis sulfate for injection in our hospital before and after intervention

作　　者：杨燕[1] 徐红青[1] 刘亚蓉[1] 徐勤[1] 黄敏燕[1] 

机构地区：[1]南通市第一人民医院,江苏南通226001

出　　处：《实用药物与临床》2012年第10期660-662,共3页Practical Pharmacy and Clinical Remedies

基　　金：江苏省南通市社会发展科技计划项目(S2010058)

摘　　要：目的评价我院注射用硫酸头孢噻利在实施干预措施后的临床应用效果。方法选择实施干预措施前(2008年8月-2009年3月)、干预后(2009年9月-2010年4月)我院123例应用注射用硫酸头孢噻利的住院患者,对抗菌药物预防性应用、用药疗程、用法用量、微生物检查及药敏试验、抗菌药物分级管理、用药频度、药物利用指数等方面进行回顾性分析与评价。结果干预后,注射用硫酸头孢噻利的临床应用仅为干预前的7.0%;干预前有44.3%的病例应用不合理,干预后无不合理应用病例;干预后,用药疗程、用法用量合理性、微生物送检率以及抗菌药物分级管理等均有明显改善,但药物利用指数(DUI)仍>1。结论实施合理用药干预措施对促进抗菌药物临床规范应用效果显著,医务科、药剂科、信息科和临床各科室应加强合作,保证抗菌药物合理用药水平持续改进。Objective To evaluate the utilization of cefoselis sulfate for injection in our hospital before and after intervention.Methods 123 cases used cefoselis sulfate for injection were analyzed and evaluated retrospectively in prophylactic use,course of treatment,usage and dosage,microbial inspection and antimicrobial susceptibility test,classified management of antibiotics,DDDs,DUI before（Aug 2008-Mar 2009）and after intervention（Sep 2009-Apr 2010）.Results After intervention,the number of cases used cefoselis sulfate for injection counted for 7% of the cases before intervention.44.3% of the cases used cefoselis sulfate for injection were unreasonable before intervention,while no case appeared after intervention.The course of treatment,rationality of the usage and dosage,microbial inspection rate and the classified management of antibiotics were obviously improved after intervention,but the DUI was not obviously improved（DUI1）.Conclusion The reasonable intervention is effective to improve the rational antibiotics use.The cooperation among the Medical Department,Pharmacy,Information section and Clinical Departments should be strengthened to ensure the rational antibiotics use at a higher level.

关 键 词：硫酸头孢噻利 抗菌药物 干预 合理用药 

分 类 号：R96[医药卫生—药理学]