斑点追踪成像评价2型糖尿病患者左心室舒张功能早期改变  

Detection of early left ventricular diastolic dysfunction in patients with T2DM by using speckle tracking imaging

作　　者：范瑞[1] 林红[1] 李翠玲[1] 姚凤娟[1] 陆堃[1] 

机构地区：[1]中山大学附属第一医院超声科中山大学超声与介入诊断研究所,广东广州510080

出　　处：《中国医学影像技术》2012年第11期1994-1998,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨斑点追踪成像(STI)技术评价2型糖尿病(T2DM)患者左心室舒张功能早期改变的价值。方法选取单纯T2DM患者39例(DM组)、T2DM合并高血压患者38例(DH组)、正常对照34名(NC组),应用STI技术测量左心室长轴三个切面及整体的纵向舒张早期峰值应变率(SrLe)、左心室三个短轴切面及整体的圆周(SrCe)及径向的舒张早期峰值应变率(SrRe)。结果 DM组和DH组的左心室SrLe均较NC组显著降低(P均<0.001),其中DH组降低更加显著(P<0.05);DM组和DH组的左心室SrCe较NC组显著降低(P均<0.05),但DM与DH组差异无统计学意义;SrRe仅在DH组显著降低(P<0.05)。结论 STI技术可以评价T2DM患者左心室舒张功能的早期改变。Objective To assess left ventricular （LV） diastolic function in patients with T2DM or combined with hyper tension with speckle tracking imaging （STI）. Methods Totally 77 T2DM patients with normal left ventricular ejection fraction （LVEF） were divided into DM group （T2DM isolated, n=39） and DH group （T2DM associated with hyperten sion, n=38 ）. Normal group included 34 healthy individuals. LV early diastolic peak longitudinal strain rate （SrLe）, early diastolic peak circumferential strain rate （SrCe） and early diastolic peak radial strain rate （SrRe） were measured using STI. Results LV SrLe was significantly lower in DM group and DH group than in normal group （both P〈0. 001）, and DH group decreased more significantly （P〈0.05）. Compared to normal group, LV SrCe was also significantly lower in DM group and DH group （both P〈0.05）, but there was no significant difference between DM group and DH group. The LV SrRe was only significantly lower in DH group than that in normal group （P〈0.05）. Conclusion STI can evaluate sub- clinical left ventricular diastolic dysfunction in longitudinal, circumferential and radial directions.

关 键 词：超声心动描记术 糖尿病 2型 心室功能 左 斑点追踪成像 

分 类 号：R540.45[医药卫生—心血管疾病]