代谢综合征与颈动脉内中膜厚度的相关性探讨  

Correlation discussion between metabolic syndrome and intima-media thickness

作　　者：廖日红[1] 谢勇[1] 

机构地区：[1]湖南省郴州市第一人民医院中心医院综合内科,湖南郴州423000

出　　处：《中国当代医药》2012年第29期181-181,183,共2页China Modern Medicine

摘　　要：目的探讨代谢综合征(MS)与颈动脉中膜厚度的相关性。方法选择2007年5月～2011年3月于本院就诊并被诊断为代谢综合征的95例患者作为研究组,同时严格按照随机化的原则选择95例健康人作为对照组,应用血管彩色超声对两组人群的颈动脉内中膜厚度(IMT)进行测定,对测定结果进行相关性分析。结果研究组IMT厚度较对照组呈明显增加趋势,差异有统计学意义(P<0.05);研究组的颈动脉粥样硬化斑块形成率为89.5%,对照组为58.9%,两组间情况比较,差异有统计学意义(P<0.05);研究组颈动脉中重度狭窄率为47.6%,对照组为11.9%,差异有统计学意义(P<0.05);血管闭塞率研究组为50.0%,对照组为0,差异有统计学意义(P<0.05)。结论患有代谢综合征的人群其颈动脉中膜厚度明显高于健康人群,可见,代谢综合征可促进颈动脉粥样硬化的发展。Objective To investigate the correlation between metabolic syndrome（MS） and intima-media thickness.Methods Ninety-five cases of patients were selected in our hospital who was diagnosed with metabolic syndrome from May 2007 to March 2011 as a research group,95 cases of healthy people were selected as control group,use color doppler ultrasound to mensurate the intima-media thickness of people in two groups.The correlation analysis of determination results were made.Results The IMT thickness of research group showed a significantly increasing trend than control group,the differ ence was statistically significant（P 0.05）;the formation rate of carotid atherosclerotic plaque in research group was 89.5%,and it was 58.9% in control group,the difference was statistically significant（P 0.05）;the rate of carotid artery severe stenosis in research group was 47.6%,and it was 11.9% in control group,the difference was statistically significant（P 0.05）;the rate of vascular occlusion in research group was 50.0%,and the control group was 0,the difference was sta tistically significant（P 0.05）.Conclusion The intima-media thickness in population with metabolic syndrome are significantly higher than the healthy population,it is thus clear that metabolic syndrome can promote the development of carotid atherosclerosis.

关 键 词：代谢综合征 颈动脉内中膜厚度 相关性分析 颈动脉粥样硬化 

分 类 号：R54[医药卫生—心血管疾病]