初均速法预测金银花的有效期  

Stable life predection for honeysuckle by initial average rate stabil ity test

作　　者：薛志平[1] 王金梅[1] 刘杰 康文艺[1] 

机构地区：[1]河南大学中药研究所,河南开封475004 [2]河南省中医研究院,河南郑州450004

出　　处：《中国中药杂志》2012年第21期3179-3181,共3页China Journal of Chinese Materia Medica

基　　金：河南省科技厅重点项目(122102310272)

摘　　要：目的:研究不同温度下金银花的稳定性,预测其室温下(25℃)的有效期。方法:采用HPLC测定金银花中绿原酸的含量,以初均速法得到其活化能Ea和分解速率常数K,预测有效期。结果:金银花在25℃下有效期为1.29年。结论:用初均速法预测金银花的稳定性,以测定绿原酸含量为指标,其操作简便,结果可靠,所以金银花在储存时应避高温,用室温保存,以保证其质量。Objective ： To study the content change of chlorogenic acid in honeysuckle under different temperature, and predict its term of validity at room temperature. Method ： The content of chlorogenic acid was assayed by HPLC. The activation energy Ea and the decomposition rate constant K were calculated by initial average rate stability tests and the prediction was carried out. Result： The stable life of honeysuckle has been determined as 1.29 years. Conclusion： The initial average rate stability test was used to predict stable life of honeysuckle, and the results are credible. Higher temperature should be avoided for honeysuckle store, and room temperature should guarantee its quality during storage.

关 键 词：初均速法 金银花 有效期 高效液相色谱法 

分 类 号：R284[医药卫生—中药学]