模拟体液法合成球形羟基磷灰石纳米粉体  

Synthesis of spherical hydroxyapatite nanopowders in simulated body fluid

作　　者：金传伟[1] 莫祥银[2] 丁毅[1] 孙卫斌[3] 冯晓叁[2] 

机构地区：[1]南京工业大学材料科学与工程学院,江苏南京210009 [2]南京师范大学分析测试中心 [3]南京大学医学院口腔医学院附属南京市口腔医院

出　　处：《无机盐工业》2012年第11期12-14,共3页Inorganic Chemicals Industry

基　　金：国家重点基础研究发展计划(973计划)资助项目(6134501ZT012004202);江苏省自然科学基金资助项目(2005CCA004;BK2007600);南京师范大学教育部留学回国人员科研启动基金资助项目(2006191XL H0132)

摘　　要：以模拟体液为溶剂,无水氯化钙(CaCl2)和磷酸氢二钾(K2HPO4·3H2O)为原料,在37℃、近中性条件下合成了球形羟基磷灰石纳米粉体,整个反应过程无须调节pH。通过XRD、FE-SEM、FT-IR和TEM等手段对粉体进行表征,结果表明:合成的产物为直径在60～80 nm的球形羟基磷灰石纳米粉体,其颗粒由直径为15 nm左右的单晶组成,且该反应产物无须烧结处理。反应时间影响晶体的结晶性,反应1 min即可获得羟基磷灰石粉体,但结晶性较弱;而反应6 h后,结晶性明显增强。Using simulated body fluid （SBF） as solvent, CaC12 and K2HPO4·3H20 as raw materials, nano-sized spherical hy- droxyapatite （HA） powders have been synthesized in almost neutral solution at 37℃ without adjusting pH during the whole reaction.The powders were characterized by XRD, FE-SEM, FT-IR, and TEM etc..Results showed that the synthesized pow- ders were nano-sized spherical hydroxyapatite with diameters between 60-80 nm, and that the particle was composed of sin- gle-crystals with the diameter of about 15 nm.Moreover, the product did not need sintering treatment.The reaction time was very important during the whole process.The HA can be synthesized in 1 min with poor crystallinity, but erystallinity became better with the reaction time increasing to 6 h.

关 键 词：模拟体液 纳米羟基磷灰石 单晶 

分 类 号：TQ126.3[化学工程—无机化工]