妊娠期肝病导致产后出血预测指标的分析  

Predicted value analysis on liver diseases in gestation period induce postpartum hemorrhage

作　　者：孙美英[1] 曲广第[1] 杨贵平 

机构地区：[1]新疆医科大学第一附属医院产科 [2]乌鲁木齐市69006部队

出　　处：《新疆医科大学学报》2012年第11期1511-1514,共4页Journal of Xinjiang Medical University

基　　金：新疆医科大学第一附属医院青年科研专项基金(2011QN09)

摘　　要：目的探讨影响妊娠期肝病发生产后出血的相关因素。方法将316例妊娠期肝病患者中发生产后出血患者62例作为研究组,未发生产后出血患者254例作为对照组,对导致产后出血的23个相关因素进行统计学分析。结果单因素分析显示,两组比较有统计学意义的因素包括:红细胞压积、总蛋白、白蛋白、门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、尿蛋白、HBsAg、有无输血、血小板、血红蛋白。经多因素Logistic回归分析显示,丙氨酸氨基转移酶(ALT)、血小板有统计学意义。结论丙氨酸氨基转移酶(ALT)升高,血小板减少是妊娠期肝病可能并发产后出血的危险因素。Objective To explore the relative risk factors with liver diseases in gestation period induce postpartum hemorrhage.Methods Clinical data of 316 patients undergoing liver diseases in gestation period were collected and analyzed retrospectively.62 patients with postpartum hemorrhage were in study group and 254 patients without postpartum hemorrhage were in control group.23 clinical factors were recruited for the study in relation to postpartum hemorrhage Data were analyzed by Logistic regression.Results Single variable analysis revealed that packed cell volume（Hct）,total protein,albumin,alanine aminotransferase（ALT）,aspartrate aminouansferase（AST）,urine protein,HBsAg,blood transfusion,platelet and maternal hemoglob exhibited significant difference（P0.05）.The result of multiple variables pair-logistic regression analysis ALT and platelet exhibited statistical significance.Conclusion The decrease of platelet,the increase of ALT are risks factor for liver diseases unique to pregnancy induce postpartum hemorrhage.

关 键 词：妊娠期 肝脏疾病 产后出血 

分 类 号：R714.25[医药卫生—妇产科学]