4例系统性红斑狼疮患者行自体外周血造血干细胞采集的护理  

Nursing for 4 systemic lupus erythematosus patients with autologous peripheral blood stem cell collection

作　　者：郑凌[1] 王好[1] 崔俊[1] 

机构地区：[1]南京军区南京总医院全军肾脏病研究所,210002

出　　处：《实用临床医药杂志》2012年第20期27-29,共3页Journal of Clinical Medicine in Practice

摘　　要：目的为拟行自体外周血造血干细胞移植的患者提供优质护理,采集足够数量的造血干细胞,降低术中及术后不良反应。方法采集前建立术前访视制度,消除患者焦虑情绪,评估患者血管条件,选择合适的血管通路方式;采集中改良抗凝策略,严密观察,预防不良反应的发生;采集后重视术后回访,进行血管通路的护理、饮食及生活指导。结果 4例患者采集终产品总量(125±29)mL,CD34+含量(2.5±1.3)×106/kg,采集后红细胞比积(HCT)下降5.6%,血小板(PLT)下降25.5%,无1例患者出现不良反应。结论全程优质护理有利于缓解患者焦虑情绪,确保足量造血干细胞的采集,为成功行干细胞移植奠定基础。Objective To provide qualified nursing for patients with autologous peripheral blood stem cell transplantation in order to reduce adverse reactions in intraoperative and postopera- tive periods, and adequate quantity of stem cells were collected as well. Methods Before collection, the preoperative interview system was established in order to eliminate patients＇ anxiety, assess pa- tients＇ vascular conditions, choose appropriate vascular access mode; during collection, a modified anticoagulation strategy was performed to prevent the occurrence of adverse reactions; after collec- tion, a return visit was important, nursing for vascular access and guidance for diet and living were necessary too. Results Total amount of collection of 4 patients was （ 125 ± 29） mL, CD34 ＋ was （2.5 ± 1.3）× 106/kg, hematocrit（HCT） after collection fell 5.6%, blood platelet （PLT） fell 25. 5 %, and no patient had adverse reactions. Conclusion Qualified nursing can relieve patients＇ anxi- ety, ensure sufficient collection of stem cell and lay the foundation for successful transplantation of stem cell.

关 键 词：系统性红斑狼疮 自体外周血造血干细胞 护理 

分 类 号：R473.5[医药卫生—护理学]