小青龙汤治疗寒哮发作期有效机制及适应范围的研究  

The effective Mechanism and Application Scope of Xiaoqinglong Decoction in Treating Attack Stage of Cold Asthma

作　　者：杨玉萍[1] 周晴[2] 舒燕萍[1] 邹云龙[2] 

机构地区：[1]江西省中医院,江西南昌330006 [2]江西中医学院,江西南昌330000

出　　处：《中国中医急症》2012年第11期1731-1732,1737,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：江西省卫生厅科研课题(2009A096)

摘　　要：目的观察小青龙汤治疗哮病发作期的有效机制及适应范围。方法将60例轻、中度的哮喘患者按发病时间分为3 d组、4～6 d组、7～10 d组。用小青龙汤治疗7、14 d,观察恶寒发热、鼻塞流涕、咳嗽、喘息、胸闷、痰量,哮鸣音改变及肺功能(FEV1、PEF)情况。结果 3组治疗后恶寒发热及鼻塞流涕、咳嗽、咯痰、胸闷、气喘、哮鸣音、FEV1、PEF均有改善,3 d组疗效最好,4～6 d组次之,7～10 d组改善程度相对不足。结论小青龙汤是通过外散表寒祛除诱因,内温伏饮以祛宿痰而控制哮病,凡有表寒实证的哮病均可应用,发病时间越短疗效越好。Objective： To observe the effective mechanism and application scope of Xiaoqinglong Decontion in treating attact stage of cold asthma. Methods： 60 patients were divided into 3 d guoup,4-6 d group,7-10 d group according to the time of onset.The changes of aversion to cold,fever, nasal obstruction,nasal discharge ,cough, dyspnea,chest distress,phlegm quantity,wheeze and pulmonary function（FEV1,PEF） were observed 7 d, 14 d af- ter treating. Results： Aversion to cold, fever, nasal obstruction, nasal discharge, cough, dyspnea, chest distress, phlegm quantity,wheeze, FEV1, PEF of three groups were all improved,while 3 d group got the best effect,4-6 d group got better effect.The effect of 7-10 d was not as good as the other groups. Conclusion： Xiaoqinglong De- coction control the asthma by the way of relieving the exterior and dispelling cold to remove inducement, and by the way of warming lung to reduce phlegm. Whatever the primary disease is, the asthma of cold superficies syn- drome can take Xiaoqinglong Decoction can be used. The shorter time of onset , the better curative effect.

关 键 词：小青龙汤 寒哮发作期 机制 适应范围 

分 类 号：R256.12[医药卫生—中医内科学]