腮腺炎致无精症患者睾丸切开取精结果与性激素水平和睾丸大小关系的研究  

Azoospermic patients caused by mumps with testicular sperm retrieval results between sex hormones and testicular size

作　　者：张水文[1] 辛楠[1] 刘军文[1] 周国萍[1] 秦似龙[1] 李建华[1] 魏岩[1] 郭军红[1] 徐野[1] 

机构地区：[1]北京军区总医院生殖医学中心,北京100700

出　　处：《临床泌尿外科杂志》2012年第11期848-850,共3页Journal of Clinical Urology

摘　　要：目的:探讨腮腺炎致无精症患者睾丸切开取精(TESA)与性激素、睾丸大小的关系。方法:52例腮腺炎致无精症患者经TESA,显微镜下观察能否找到活动的精子,电化学方法方法测定性激素(FSH、LH、T、PRL、E2)的水平,超声测量并计算睾丸体积。结果:52例患者TESA找到活精子38例(73.1%),血清FSH和LH水平,无精子组平均数明显高于有精子组,两间差异有统计学意义(P<0.05),血清T、E2、PRL组间差异无统计学意义。睾丸体积无精子组平均数小于有精子组,但组间差异无统计学意义(P>0.05)。以FSH值为标准,38例可找到活动精子患者中,正常范围之内的有23例(44.2%),高出正常值2倍范围内的有11例(21.2%),2倍范围之外的有4例(7.7%)。以睾丸体积为标准,38例可找到活动精子患者中,睾丸体积≥6ml有35例(67.3%),睾丸体积<6ml有3例(5.8%)。结论:睾丸体积和FSH水平可以作为腮腺炎致无精症患者预判取精成功概率的指标,所有患者都应该TESA,为单精子卵胞浆内注射创造机会。Objective： To investigate the relation between testicular sperm retrieval （TESA） in azoospermia caused by mumps and sex hormones and testicular size. Method：Fifty-two cases of azoospermic patients caused by mumps with TESA, under the microscope can find the sperm of the activities, the electrochemical method meas- ured sex hormones （FSH, LH, T, PRL, E2） level, ultrasound and calculate the testicular volume. Result.. Fifty- two cases of male patients with testicular sperm retrieval to find 38 cases of live sperm, sperm retrieval rate was 73.1%, serum FSH and LH levels, non-sperm group was significantly higher than sperm groups, and between the two groups was statistically significant （P〈0.05）, serum T, E2, PRL was not statistically significant. Tes- ticular volume, non-sperm group average of less than sperm group, but no statistically significant between the two groups （P〉0.05）. FSH value criteria, 38 cases can be found in patients with motile sperm in 23 cases （44.2%） within the normal range, higher than the normal two-fold range in 11 cases （21.2% ）, 2 times outside the scope of 4 cases （7.7%）. Testieular volume, 38 cases can be found in patients with motile sperm, testicular volume ≥ 6 ml of 35 cases （67.3%）, testicular volume 〈6 ml three cases （5.8%）. Conelusion：Testicular volume and FSH levels can be used as mumps induced azoospermia patients to predict the probability of success of sperm retrieval indicators, all patients should have a testicular biopsy, and create opportunities for ICSI.

关 键 词：腮腺炎 无精症 性激素 睾丸大小 

分 类 号：R697[医药卫生—泌尿科学]