姜附通痹合剂治疗膝骨关节炎108例临床分析  

Analysis of Knee Osteoarthritis Treatment Effect on 108 Cases of Ginger with Tongbi Mixture

作　　者：刘金福[1] 侯丽萍[1] 康俊萍 高雪灵 李婧霞 雷娜[1] 

机构地区：[1]太原市类风湿病医院,山西太原030006 [2]柳林县中医院,山西柳林033300

出　　处：《山西职工医学院学报》2012年第5期41-43,共3页Journal of Shanxi Medical College for Continuing Education

摘　　要：目的:观察姜附通痹合剂治疗膝骨关节炎的临床疗效及作用机理。方法:将2009年1月1日至2011年12月31日入院的膝骨关节炎患者随机分成两组,治疗组服用补肾通督胶囊及姜附通痹合剂,对照组服用补肾通督胶囊及双氯酚酸钠缓释胶囊。4周后,观察两组治疗前后双膝关节的疼痛、肿胀、压痛、关节屈伸活动及全身症状与不良反应。结果:两组关节临床症状治疗后均较治疗前明显减轻,与治疗前比较差异有统计学意义(P<0.05),治疗组总有效率为97.2%,对照组总有效率为84.1%,治疗组总有效率高于对照组(P<0.05),治愈率及显效率优于对照组(P<0.05)。治疗组在治疗后关节疼痛、肿胀、畏寒方面的改善明显优于对照组(P<0.05);对照组不良反应例数多于治疗组(P<0.05)。结论:姜附通痹合剂治疗膝骨关节炎有明显的临床疗效。Objective： To observe the clinical efficacy and mechanism of action of Ginger with tongbi mixture on knee osteoarthritis. Methods： 108 patients with knee osteoarthritis from January 1, 2009 to December 31, 2011 were randomly di- vided into two groups. The treatment group was given the Bushen Tongdu capsules and Ginger with tongbi mixture, and the control group a kidney Tongdu capsule and diclofenac sodium sustained-release capsules. The course of treatment for the two groups were observed for four weeks. Pain, swelling, tenderness, joint range of motion and systemic symptoms of adverse re- actions on both knees were observed before and after the treatment. Results： The clinical symptoms of the joints in the two groups both reduced significantly after treatmen （P 〈0.05）. The total effective rate of treatment group was 97.2% and the control group 84. 1%. The total effective rate of treatment group is better than the control group （ P 〈0. 05）, especially the cure rate and effectual rate were significantly better than the control group （P 〈 0.05）. The treatment effect on joint pain, swelling and fear cold cure rate of treatment group （P 〈 0.05 ） was significantly better than the control group （P 〈 0.05 ）. The cases of adverse reactions in the control group were more than the treatment group （P 〈 0.05 ）. Conclusion： The clinical effi- cacy on knees osteoarthritis by Ginger with tongbi mixture could be conspicuous.

关 键 词：姜附通痹合剂 双氯酚酸钠缓释胶囊 膝骨关节炎 

分 类 号：R289.5[医药卫生—方剂学]