猪腹股沟/阴囊疝易感位点定位及其候选基因研究进展  

Advances in Susceptibility Loci and Candidate Genes for Pig Inguinal/Scrotal Hernias

作　　者：阮国荣[1,2] 肖石军[2] 幸宇云[2] 丁能水[2] 

机构地区：[1]福建农业职业技术学院,福建福州350119 [2]江西农业大学动物生物技术国家重点实验室培育基地,江西南昌330045

出　　处：《中国畜牧杂志》2012年第21期88-92,共5页Chinese Journal of Animal Science

基　　金：国家自然科学基金(31071089)

摘　　要：腹股沟／阴囊疝是猪最常见的遗传缺陷之一，每年给世界养猪业造成巨大的经济损失，其发病率一般在1．7％～6．7％，但在不同的品种和群体间有较大差异。已有研究表明，猪腹股沟／阴囊疝的发生主要受遗传因素影响，本文综述了猪腹股沟／阴囊疝疾病易感位点和相关侯选基因的研究进展，旨在为系统解析猪猪腹股沟／阴囊疝的分子遗传及病理机制提供参考，并对发展抗猪腹股沟／阴囊疝分子育种技术提出展望。Pig inguinal/scrotal her nia is one of the most common congenital disorders in pigs and causes huge economic loss in the pig industry. The prevalence of pig inguinal/scrotal hernia varies from 1.7% to 6.7% in different breeds and population. It has been estimated that genetic effects play important roles in the occurrences of these defects. To better understand the molecular and pathological mechanism of this disease and develop molecular breeding technologies for selections against inguinal/scrotal hernia in pigs, we reviewed the identification of susceptibility loci and candidate genes for pig inguinal/scrotal hernias.

关 键 词：腹股沟 阴囊疝 数量性状位点(QTL) 候选基因 猪 

分 类 号：S828.2[农业科学—畜牧学]