正交试验法优选栀子豉汤的水提工艺  

Optimization of Water Extraction Process for Zhizichi Decoction

作　　者：王虹玉[1] 喇孝瑾[1] 白素芬[1] 喇万英[1] 吕建东[1] 张晓鹏[1] 周瑞华[1] 

机构地区：[1]河北联合大学,河北唐山063000

出　　处：《中国实验方剂学杂志》2012年第22期36-38,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技部国际合作项目(2008DFA31050)

摘　　要：目的:优选栀子豉汤的水提工艺。方法:以栀子苷的含量为指标,采用HPLC测定指标成分含量,通过正交试验设计考察加水量、提取次数、提取时间等因素对栀子豉汤水提工艺的影响。结果:最佳水提工艺是加8倍量水提取2次,每次20 min。结论:该优选的提取工艺效率高、简便、安全。Objective： To optimize water extraction process of zhizichi decoction. Method： With the content of geniposide as index which was determined by HPLC, orthogonal test design was adopted to investigate influence of extraction times, extraction time and the amount of water on water extraction technology of Zhizichi decoction. Result： The best extraction technology conditions were as follows： extracted 2 times with 8 times the amount of water for 20 minutes per time. Conclusion： This optimized extraction process was efficient, safe, simple.

关 键 词：栀子豉汤 栀子苷 栀子 正交试验 高效液相色谱法 

分 类 号：R283.6[医药卫生—中药学]