中药防治鸡传染性支气管炎存在的问题及对策  

Problems in Prevention and Treatment of Infectious Bronchitis with Traditional Chinese Medicine and the Counter Measures

作　　者：王玲[1] 陈炅然[1] 郭天芬[1] 李宏胜[1] 杨峰[1] 胡广胜[2] 周绪正[1] 牛建荣[1] 

机构地区：[1]中国农业科学院兰州畜牧与兽药研究所 农业部兽用药物创制重点实验室 甘肃省新兽药工程重点实验室,甘肃兰州730050 [2]甘肃农业大学动物医学院,甘肃兰州730070

出　　处：《中国动物检疫》2012年第11期61-63,共3页China Animal Health Inspection

基　　金：中央级公益性科研院所基本科研业务费专项资金项目(BRF090405);中央级公益性科研院所基本科研业务费专项资金项目(BRF090403)

摘　　要：鸡传染性支气管炎(IB)疫苗缺乏交叉免疫或完全无交叉免疫,发病后无特效药物治疗。有些中药具有抑杀病毒的作用,且能调节机体的免疫功能,具有非特异性的抗病毒功能,用于鸡IB的临床防治收效甚好,所用方剂与西药相比具有独特的优势。本文针对研发防治鸡传支中药存在的主要问题,探讨了研究的思路和途径,应避免仅对草拟方剂做简单的临床验证,需要对中药方剂的药效学、药理学、药代动力学、毒理学、中药化学及作用机理做深入研究,以及科学严谨的试验设计支持,大量试验数据证明,以期进一步完善并扩大中药在防治畜禽传染性疾病上的应用。The infectious bronchitis （IB） vaccines lack of cross immunity or have no cross immunity, and there is no specific drug for IB cases. Some traditional Chinese medicine （TCM） has virucidal effect, can adjust the immune function, has nonspecific antiviral function, and has good results and unique advantages compared with Western medicine in clinical prevention and treatment of IB. This paper is focused on the problems in research and development of TCM to control IB and discuss the research thinking and way, and suggests that the simple clinical validation for draft prescription should be avoided, the pharmacodynamics, pharmacology, pharmacokinetics, toxicology, TCM chemistry and mechanism should be studied in-depth way, and it is necessary to have strict scientific test design and test data, in order to further improve and expand the application of TCM in the prevention and treatment on livestock and poultry infectious diseases.

关 键 词：鸡传染性支气管炎 中药方剂 防治 

分 类 号：S852.31[农业科学—基础兽医学]