听性脑干诱发电位在手足口病中的运用  

Clinical application of auditory brainstem response in hand-foot-mouth disease

作　　者：罗序峰[1] 周涛[1] 刘玉玲[1] 朱建萍[1] 吴涛[1] 张胜[1] 姜玉娥[1] 龙晓玲[1] 马立忠[1] 付四毛[1] 

机构地区：[1]中山市博爱医院儿科,广东中山528400

出　　处：《临床儿科杂志》2012年第11期1074-1077,共4页Journal of Clinical Pediatrics

基　　金：中山市科技局重大项目(No.20101A008)

摘　　要：目的探讨听性脑干诱发电位(ABR)在手足口病中的临床运用价值。方法对住院的200例普通手足口病患儿及100例重症手足口病患儿进行ABR检查,并对结果异常的患儿进行随访。结果 200例普通手足口病患儿中,177例ABR检查正常,9例仅为听阈值异常,14例为脑干功能受损。100例重症手足口病患儿中19例仅为听阈值异常,60例为脑干功能受损。14例脑干功能受损的普通手足口病患儿中有10例进展为重症手足口病,2周后复查均恢复正常。重症手足口病患儿19例仅为听阈值异常者出院2周后复查恢复正常,而60例脑干功能受损患儿中有37例在出院2周后恢复正常,10例于1个月后恢复正常,7例于3个月后恢复正常,死亡2例,现仍有4例在随访中。结论 ABR检查可对脑干功能受损进行早期辅助诊断,判断手足口病患儿预后及作为随访的一个指标。Objective To explore the clinical application of auditory brainstem response （ABR） in patients with hand- foot -mouth disease （HFMD）. Methods Two hundred （200） ordinary inpatients with HFMD and 100 patients with severe HFMD were included in this study and their ABR were measured and the patients with positive results were followed up. Results In 200 ordinary patients, 177 showed normal ABR, 9 presented abnormal hearing threshold and 14 showed brainstem dysfunction. Among 100 severe HFMD patients, 19 showed abnormal hearing threshold and 60 showed brainstem dysfunc- tion. Ten of 14 ordinary patients with brainstem dysfunction progressed to severe HFMD and their ABR returned to normal in 2 weeks. Nineteen severe HFMD patients with abnormal hearing threshold and 37 of 60 patients with brainstem dysfunction returned to normal 2 weeks after discharge from hospital, but 10 patients recovered in a month and another 7 patients became normal in 3 months. Up till now, 4 cases are still in the following-up. Conclusions ABR can be adapted to evaluate the prog- nosis of brainstem dysfunction as an adjunctive diagnosis and a marker of follow-up of HFMD.

关 键 词：手足口病 听性脑干诱发电位 预后 

分 类 号：R725.1[医药卫生—儿科]