睾丸CR16与精子发生  

Testicular CR16 and spermatogenesis

作　　者：符小春[1] 相文佩[1] 

机构地区：[1]华中科技大学同济医学院计划生育研究所,湖北武汉430030

出　　处：《中华男科学杂志》2012年第11期1032-1035,共4页National Journal of Andrology

摘　　要：精子发生是依靠各种激素(FSH、LH、T、17β雌二醇)、细胞因子和基因调节的复杂调控过程。基因调控在精子发生中的研究已逐渐成为热点,已发现的与精子发生相关的基因,如AYZ、DAZ、YRRM、NOSTRIN等。但目前关于CR16在男性生殖方面的报道尚不多见,其在精子发生中的作用机制并不十分清楚,本文主要从支持细胞形成血睾屏障角度,对CR16在男性生殖系统精子发生中的研究做一综述。Spermatogenesis is a complex regulatory process depending on a variety of hormones （such as FSH, LH, T, and 1713 estradiol）, cytokines, and genes. Research on gene regulation in spermatogenesis has become a hot spot and revealed some spermato- genesis-related genes, such as AYZ, DAZ, YRRM, NOSTRIN, and so on. Reports are rarely seen on the role of CR16 in male repro- duction, and its action mechanism in spermatogenesis is not yet clear. This article updates the role of CR16 in spermatogenesis in the male reproductive system from the perspective of Sertoli cells forming a blood-testis barrier.

关 键 词：CR16 血睾屏障 支持细胞 男性生殖 精子发生 

分 类 号：R698.2[医药卫生—泌尿科学]