Adapta起搏器减少右心室起搏的临床研究  

Clinical study of Adapta pacemaker reducing right ventricular pacing

作　　者：李腾[1] 游琼[1] 吴铿[1] 

机构地区：[1]广东医学院附属医院心内科,广东湛江524001

出　　处：《临床心血管病杂志》2012年第11期818-820,共3页Journal of Clinical Cardiology

摘　　要：目的:对比Adapta起搏器和SDR303起搏器在减少不必要的右心室起搏方面的有效性和安全性。方法:对39例病态窦房结综合征患者,分别植入具有心室起搏管理功能的Adapta起搏器(Adapta组,18例)和SDR303起搏器(SDR303组,21例)。随访12个月,观察2组右心室起搏比例、心房颤动(房颤)发生情况和超声心动图改变。结果:Adapta组术后1个月、3个月、6个月及12个月的心室累积起搏百分比显著低于SDR303组[(0.30±0.23)%:(13.70±3.65)%,(0.36±0.14)%:(16.94±5.42)%,(0.36±0.19)%:(29.22±5.40)%,(0.32±0.19)%:(33.11±5.92)%,均P<0.05];SDR303组心室起搏比例随时间延长而逐渐增加。随访12个月,Adapta组无房颤发生,SDR303组5例(23.8%)发生阵发性房颤。2组术后6个月、12个月的超声心动图参数分别与术前比较,均差异无统计学意义。结论:相比于SDR303起搏器,Adapta起搏器能显著减少不必要的右心室起搏,同时并不增加患者房颤、心力衰竭和死亡的风险。Objective：To explore the safety and efficacy of Adapta pacemaker reducing right ventricular pacing compared with SDR303 pacemaker.Method：Thirty-nine sick sinus syndrome patients were divided into Adapta group（n=18） and SDR303 group（n=21）.The cumulative percentage of ventricular pacing（Cum%VP）,atrial fibrillation events and echocardiographic parameters were observed after 12 months＇ follow-up.Result ： Cum % VP in Adapta group at 1,3,6,12 months after procedure were significantly lower than those in SDR303 group [（0.30 ± 0.23） % vs（13.70 ±3.65） %,（0.36 ± 0.14） % vs（16.94 ± 5.42） %,（0.36 ± 0.19） % vs（29.22 ± 5.40） %,（0.32 ± 0.19） % vs（33.11 ± 5.92） %,all P 0.05].Cum% VP of SDR303 group increased with time.During follow-up of 12 months,no one had atrial fibrillation in Adapta group,and 5 patients（23.8%） had paroxysmal atrial fibrillation in SDR303 group.Echocardiographic parameters of both groups at 6,12 months after procedure didn＇t change significantly compared with before procedure respectively.Conclusion： Compared with SDR303 pacemaker,Adapta pacemaker can significantly reduce the unnecessary right ventricular pacing,and doesn＇t increase the risk of atrial fibrillation,heart failure and death.

关 键 词：心房颤动 Adapta起搏器 右室起搏 心室起搏管理 

分 类 号：R541.7[医药卫生—心血管疾病]