Nucleus24型人工耳蜗不同刺激部位电诱发复合动作电位分析  

Site of cochlear stimulation and its effect on electrically evoked compound action potentials using the Nucleus24 cochlear implants

作　　者：田颖[1] 李巍[1] 王铮[1] 杨宁[1] 惠莲[1] 姜学钧[1] 

机构地区：[1]中国医科大学附属第一医院耳鼻咽喉科.沈阳110001

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第22期1014-1016,1019,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:应用神经反应遥测(NRT)技术测试,探讨刺激耳蜗不同部位电诱发复合动作电位(ECAP)的特点。方法:应用NRT软件对27例Nucleus CI24R(CA)儿童植入者进行术中记录,分别测试每一位患者的第1、4、8、11、17、22号电极,幅值增长函数进行线性拟合,确定ECAP阈值、幅值及幅值增长曲线斜率,比较耳蜗顶部、中部、底部不同刺激部位之间ECAP的差异。结果:ECAP阈值自蜗底至蜗顶呈下降趋势,反应幅值自蜗底至蜗顶呈上升趋势,幅值增长曲线斜率自蜗底至蜗顶呈上升趋势。结论:刺激耳蜗不同部位ECAP阈值、幅值及幅值增长曲线斜率显著不同。Objective：Using the neural response telemetry（NRT） software to investigate whether a difference exists in ECAP properties depending on the region of the cochlea that is stimulated and measured.Method：Twenty seven Nucleus CI24R（CA）cochlear implant users participated in this study.ECAPs were recorded intraoperatively using the NRT software.No.1、4、8、11、17、22 electrodes were tested for each patient.ECAP amplitude,threshold and slope were measured using amplitude growth sequences.Result：Apical recordings showed on average higher ECAP amplitudes,lower ECAP thresholds and steeper slopes of the ECAP amplitude growth function.Conclusion：Considerable variability exists in ECAPs due to the region of the cochlea that is stimulated and measured.

关 键 词：耳蜗植入 动作电位 神经反应遥测 

分 类 号：R764.35[医药卫生—耳鼻咽喉科]