妊娠哺乳期骨质疏松的研究进展  

The Research Progress of Pregnancy and Lactation Osteoporosis

作　　者：王永丰[1] 韩瑛[1] 王达义[1] 

机构地区：[1]湖北医药学院附属太和医院脊柱外科,湖北十堰442000

出　　处：《医学综述》2012年第20期3407-3409,共3页Medical Recapitulate

摘　　要：妊娠哺乳期骨质疏松的发病原因未明,钙和维生素D等营养素相对不足、内分泌改变、妊娠状态及遗传因素等可能是致病的重要因素。因其发生在妊娠哺乳期,一旦因骨质疏松继发骨折,可严重降低孕妇的生活质量,且其对胎儿和婴儿产生重大影响。最近研究证实,双膦酸盐合并雷奈酸锶治疗哺乳期骨质疏松患者效果良好。现就妊娠哺乳期骨质疏松的病因、病理生理、临床表现与治疗等方面进行综述,以便更好地为临床和科研提供依据。Pregnancy and lactation-associated osteoporosis refers to osteoporosis in pregnancy and lactation in women with acute low-back or hip thigh pain,which may be associated with dysfunction in idiopathic osteoporosis.Its etiology is not clear yet,while relatively insufficient calcium and vitamin D and other nutrientsare,hormonal changes,pregnancy status and genetic factors may be the pathogenic factors.Because of its onset in pregnancy and lactation,once fractures secondary to osteoporosis happens pregnant women′s quality of life will be severely affected,and the fetus/infant will be significantly impacted.Recent research confirms that bisphosphonates with strontium ranelate treatment during lactation in osteoporotic patients have good results.Here is to make a review on the etiology,pathophysiology,clinical manifestations and treatment of the osteoporosis during pregnancy and lactation,in order to provide references for the clinical and scientific research.

关 键 词：骨质疏松 妊娠 哺乳 骨量 钙 

分 类 号：R816.8[医药卫生—放射医学]