慢性阻塞性肺疾病患者气道壁厚度与肺功能的关系  

Chronic obstructive pulmonary disease patients with airway wall thickness and the relationship between the pulmonary function

作　　者：何一曼[1] 王镇山[2] 

机构地区：[1]大连市友谊医院呼吸科,辽宁大连116001 [2]大连医科大学附属第二医院呼吸科,辽宁大连116023

出　　处：《中外医疗》2012年第31期53-54,共2页China & Foreign Medical Treatment

摘　　要：目的研究慢性阻塞性肺疾病患者支气管壁厚度与肺功能的相关性。方法用高分辨率CT扫描14例COPD患者和16例对照组。测量右上叶尖段支气管起始部位的管壁内径及外径,算出管壁厚度、管壁厚度与外径比值、气道壁总面积及总面积的比值。评估这些指标与肺功能的相关性。结果慢性阻塞肺疾病组与对照组比较,上述指标较对照组明显增厚。且与肺功能各项指标有显著的相关性。结论高分辨率CT可测量气道壁厚度,并能评估气流受限的程度。Objective To study the correlation between the thickness of airway and lung function in patients with COPD.Methods High-resolution CT（HRCT） scaning was performed in 14 patients with COPD and 16 healthy controls.The airway diameter and lumen diameter were measured at the starting site of the right apical bronchus.Thickness of airway wall,the ratio of airway wall thickness and airway diameter,the percentage of the airway wall area of the total cross-sectional area of the airway and the total area of the airway wall were calculated by the formula.The correlation between the HRCT measurements and the lung function were assessed.Results The airway wall is thicker in COPD group than normal control group.There are correlations between the HRCT measurements and lung function.Conclusion The airway wall can be measured and assessed by HRCT which are sensitive in the evaluation of ariflow limitation.

关 键 词：慢性阻塞性肺疾病 气道壁增厚 高分辨率CT 肺功能 

分 类 号：R4[医药卫生—临床医学]