神经节苷脂联合奥扎格雷钠对急性脑梗死疗效观察  

Observation and analysis of the effects of ganglioside combined with ozagrel in the treatment of acute cerebral infarction

作　　者：许敬菊[1] 程慎令[1] 

机构地区：[1]滕州市中心人民医院药学部,山东滕州277500

出　　处：《中国医院药学杂志》2012年第22期1829-1830,1852,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:观察神经节苷脂联合奥扎格雷钠在急性脑梗死治疗中的疗效及其安全性。方法:对120例急性脑梗死患者分别进行奥扎格雷钠及其与神经节苷脂的联合治疗,通过NIHSS评分和BI指数对疗效及其安全性进行评估。结果:2组患者疗效显著,联合治疗组有效率高达90%,效果明显优于对照组(78.33%),无效患者(10.00%)则明显少于对照组(21.67%);治疗后患者生活能力均有显著提高(P<0.05),治疗组提高更为明显(P<0.01);治疗中患者生理指标平稳,未见明显不良反应。结论:神经节苷脂与奥扎格雷钠治疗急性脑梗死疗效显著,具有可靠的安全性。OBJECTIVE To analyze the efficacy and safety of ozagrel combined with ganglioside therapy in the treatment ofacute cerebral infarction. METHODS 120 patients with acute cerebral infarction were selected and randomly divided into two groups, namely the control group and treatment group, n = 60 cases, the control group was given ozagrel, and the combined treatment group was given ganglioside, the two groups of patients were observed by NIHSS score and the BI index of the effi- cacy and safety assessment. RESULTS There were significant efficacies in both groups of patients, combined treatment group was better than the control group; viability was significantly improved, and no significant adverse reaction was discovered. CONCLUSION The therapeutic efficacy of ganglioside combined with sodium ozagrel treatment for acute cerebral infarction is significant, with reliable security.

关 键 词：神经节苷脂 奥扎格雷钠 急性脑梗死 疗效 安全性 

分 类 号：R972[医药卫生—药品]