湖北羊蹄甲的化学成分研究  

The Chemical Constituents of Bauhinia glauca(Wall. ex Benth.) Benth. subsp. hupehana(Craib) T.Chen

作　　者：白明安图[1] 任凤霞[2] 杨郁[2] 张杨[2] 屈爱桃[1] 赵毅民[2] 

机构地区：[1]内蒙古医学院,呼和浩特010059 [2]军事医学科学院毒物药物研究所,北京100850

出　　处：《中国药学杂志》2012年第22期1796-1798,共3页Chinese Pharmaceutical Journal

摘　　要：目的研究湖北羊蹄甲[Bauhinia glauca(Wall.ex Benth.)Benth.subsp.hupehana(Craib)T.Chen]茎叶的化学成分。方法植物材料经丙酮冷浸提取,色谱法分离化学成分,根据其波谱数据鉴定化合物结构。结果分离鉴定了5个化合物,分别为4-甲氧基新异甘草苷(1),bauhiniasin(2),硫黄菊素(3),异甘草素(4),4'-甲氧基新甘草苷(5)。结论其中化合物1为新天然产物,化合物2,4为本植物首次分离,化合物3,5为本属首次分离。OBJECTIVE To study the chemical constituents of the stem and leaves of Bauhinia glauca （ Wall. ex Benth. ） Benth. subsp, hupehana （Craib） T. CheM. METHODS The plant material was extracted with acetone at room temperature. The chemical constituents were isolated by chromatographic methods and their structures were identified by spectroscopic analysis. RE- SULTS Five compounds were obtained and identified as （2＇, 4＇-dihydroxy-4-methoxychalcone）-4＇-β-D-glucoside （1）, bauhiniasin （ 2）, sulfuretin （ 3 ）, isoliquiritigenin （4）, and 4＇-methylglucoliquiritigenin （5）. CONCLUSION Compound 1 is a new natural prod- uct, and this is the first time to find compounds 2 and 4 in this plant and compounds 3 and 5 in this genus.

关 键 词：湖北羊蹄甲 4-甲氧基新异甘草苷 查耳酮 橙酮 二氢黄酮 

分 类 号：R284[医药卫生—中药学]