濮阳市2008—2012年手足口病流行病学特征分析  

Epidemiological features of hand,foot and mouth disease in Puyang in 2008—2012

作　　者：王志彬[1] 李言彬[1] 王晓利[1] 

机构地区：[1]河南省濮阳市疾病预防控制中心,河南濮阳457000

出　　处：《微生物学免疫学进展》2012年第5期63-67,共5页Progress In Microbiology and Immunology

摘　　要：目的了解濮阳市手足口病流行病学特征,为制定防控策略提供科学依据。方法通过国家疾病监测信息管理系统收集的全市2008—2012年6月6日手足口病疫情资料进行描述和分析,并对部分病例和重症病例标本进行肠道病毒病原学检测。结果全市共报手足口病16 492例,发病高峰是每年的3-5月(第12～20周),呈典型的单峰型曲线;发病年龄以0～4岁居多;男性多于女性;散居儿童多于托幼机构儿童,爆发病例多发生在托幼机构,手足口病病原有EV71、CoxA16和其他肠道病毒,以EV71和CoxA16为主。结论手足口病发病有明显的季节性、年龄和性别差异,小年龄组儿童是手足口病预防控制重点人群,流行年度和流行季节的优势毒株为EV71,重症患者中EV71占到86.35%;非流行年和季节手足病例主要由CoxA16和其他肠道病毒引起。手足口病防控重点应体现在对病例分类管理上,同时应继续加强重症病例疫情监测和爆发控制。Objective To analyze the epidemiological features of hand, foot and mouth disease （HFMD） in Puyang from 2008 to 2012. Methods A descriptive epidemiologic analysis was used in analyzing for the data of HFMD cases in Puyang by the Infectious Disease Reporting Information System from 2008 to June 6, 2012. The detection for Entericvirus etiology was carried out in some cases and severe cases. Results There were 16 492 reported HFMD cases from 2008 to 2012. The epidemic period was from March to May （ 12th to 20th week） , and it appeared as a typical single peak. HFMD cases were mainly concentrated in children ≤ 4 years old. The male cases were obviously higher than female cases. The cases were higher in scattered children than those in children at childcare center in which there were more accumulative cases in outbreak. Enterovirus 71 （ EV71 ） and Coxsackievirus A16 were both the major etilolgical agents of HFMD. Conclusion The occurrence of HFMD for groups of different age and sex, as well as seasons were different. It is younger age group that is the major target to control and prevent HFMD. The prevalent strain was EV71 in this epidemic period, by which 86.35% of the severe cases were infected. HFMD cases were mainly infected by Coxsackievirus A16 and other enterovirus in non-epidemic years and periods. Classified management to the cases is a crucial measure in prevention and control of HFMD, at the same time, it should enhance the monitoring to severe cases and controlling the outbreak of the disease.

关 键 词：手足口病 肠道病毒 肠道病毒71型 柯萨奇病毒A16型 

分 类 号：R725.1[医药卫生—儿科]