不同序列核磁共振成像与光相干生物测量仪测量正常健康者眼轴长度比较  

Comparison of axial length between different magnetic resonance imaging and IOL Master in emmetropic eyes

作　　者：闻彩云[1] 蒋丽琴[2] 黎金林[1] 朱姬莹[1] 

机构地区：[1]温州医学院附属第一医院放射科,325000 [2]温州医学院附属眼视光医院

出　　处：《中华眼底病杂志》2012年第6期598-601,共4页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的对比分析不同序列核磁共振成像（MRI）与光相干生物测量仪（IOLMaster）测量正常健康者的眼轴长度（AL）差异及其相关性。方法经裂隙灯显微镜、直接检眼镜及屈光度检查确定双眼正视眼的健康志愿者67名纳入研究。其中，男性30名，女性37名；年龄8～21岁，平均年龄14．9岁。所有受检者行横轴位（AX）及矢状斜位（OS）脂肪抑制的快速自旋回波（FSE）T，加权成像（WI）、脂肪抑制的FSET2WI、液体衰减翻转恢复序列（FLAIR）T2wI及快速扰相梯度回波序列（FsPGR）T-wI的MRI检测；同时行IOLMaster检测。对比分析不同序列MRIAL测量值与IOI。MasterAL测量值的差异及其相关性。结果AX和0s的FSET。WI、FSET2WI、FLAIRT2WI、FSPGRT。wIAL测量值分别为（24．14士0．81）、（24．26±0．81）、（23．87士0．79）、（24．11士0．82）、（24．08士0．86）、（24．22士0．81）、（23．84±0．79）、（24．03±0．81）mm，IOLMasterAL测量值为（23．91±0．80）mm。不同序列MRIAL测量值分别与10LMasterAL测量值比较，差异均有统计学意义（t=－13．54、－23．20、4．08、－15．55、－8．00、－23．22、5．25、－10．62，Pd0．01）。AX、OS的AL各测量值与IOLMasterAL测量值均具有显著相关性（r＝0．97、0．96、0．98、0．97、0．96、0．80、0．98、0．97，P〈0．01）。结论不同序列MRIAL测量值与10LMasterAL测量值均有差异，且具有显著相关性。Objective To analyze the correlation and difference of axial length （AL） measurements by comparing magnetic resonance imaging （MRI） of different pulse sequence with IOL Master of normal eyes. Methods The 67 emmetropic volunteers were selected by the slit lamp microscope, direct ophthalmoscope and refractive examination in this study. The patients included 30 males and 37 females. The patients＇ ages ranged from eight to 21 years, with a mean age of 14.9 years. Fast spin echo （FSE） TlWI, FSE T2WI, fluid attenuated inversion recovery （FLAIR） T2WI, FSPGR TIWI were performed. The axial （AX） and oblique sagittal （OS） sections were taken and the AL from MRI section with different sequences were measured. The AL taken by IOL-Master was used as standard. The difference and correlation between measurements of two methods were analyzed. Results The AL of AX FSE TlWI, AX FSE T2WI, AX FLAIR T2 WI, AX FSPGR TlWI, OS FSE T1 WI, OS FSE T2 WI, OS FLAIRT2 WI and OS FSPGR T1WI were （24.14±0.81）, （24.26±0.81）, （23.87±0.79）, （24. 11±0.82）, （24.08±0.86）, （24.22±0.81）, （23.84±0.79） and （24.03±0.81） mm, respectively. The AL of IOL-Master was （23.91±0.80） mm. The differences of AL between IOL-Master and various MRI sequences were statistically significant （t =-13.54, -23.20, 4.08, -15.55,-8.00, -23.22, 5.25, -10.62; P〈0.01）. There were excellent correlations between IOL-Master and various MRI sequences （r=0.97, 0.96, 0.98, 0.97, 0.96, 0.80, 0.98, 0.97; P 〈 0.01）. Conclusion There are differences and significant correlations between MRI sequences and IOL-Master.

关 键 词：磁共振成像 体层摄影术 光学相干 

分 类 号：R445.2[医药卫生—影像医学与核医学]