刺梨多糖铁(Ⅲ)配合物的合成及其铁含量的测定  

Synthesis of Rose Roxburghii Tratt Polysaccharide-Fe(Ⅲ)Complex and Determination of Fe

作　　者：赵文阳[1] 孙丙政 陈穆彦[1] 王云峰[3] 杜薇[1] 

机构地区：[1]贵阳中医学院,贵州贵阳550002 [2]济南三株福尔制药有限公司技术部,山东济南251402 [3]陕西渭南职业技术学院医学院,陕西渭南714000

出　　处：《辽宁中医杂志》2012年第11期2256-2257,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：贵州省中药现代化专项项目(黔科合中药字[2010]5024号)

摘　　要：目的:从刺梨中提取刺梨多糖,将其与铁(Ⅲ)合成多糖铁复合物(RPC),建立RPC中铁含量的测定方法。方法:热水浸泡法提取刺梨多糖;在碱性条件(pH=8.0),刺梨多糖水溶液与三氯化铁反应合成制备刺梨多糖铁RPC,邻菲罗啉分光光度法测定RPC中铁(Ⅲ)的含量。结果:RPC为红褐色的无定型粉末,RPC中铁(Ⅲ)的含量为23.30%。结论:为刺梨多糖铁口服补铁剂的研究提供了基础。Objective：Rose roxburghii Tratt polysaccharide was extracted from Rose roxburghii Tratt,then Roseroxburghii Tratt polysaccharide-Fe（Ⅲ） complex（RPC） was synthesized with Rose roxburghii Tratt polysaccharide and FeCl3.The study established the method of determination of iron in RPC.Methods：Rose roxburghii Tratt polysaccharide was Abstracted with warm water.RPC was synthesized with Rose roxburghii Tratt polysaccharide and FeCl3,under the alkaline condition（pH=8.0）.At last the Fe（Ⅲ） content in RPC was detected by phenanthroline spectrophotometry.Results：RPC was heavy brownish red and shapeless powder.The content of Fe（Ⅲ） in RPC was 23.30% detected by phenanthroline spectrophotometry.Conclusion：It provides a basis for the Oral supplement iron agent of Rose roxburghii Tratt polysaccharide-Fe（Ⅲ）

关 键 词：刺梨多糖 刺梨多糖铁配合物 铁含量测定 

分 类 号：R927.2[医药卫生—药学]