无碱条件下由芳香醛肟和磺酰氯制备O-磺酰基芳香醛肟  

Base-Free Method for Preparation of O-Sulfonyl Aldoximes Starting from Aldoximes and Sulfonyl Chlorides

作　　者：邓桂胜[1,2] 莫宏华[1] 罗景[1] 汤力[1] 

机构地区：[1]湖南师范大学化学化工学院,长沙410081 [2]化学生物学及中药分析教育部重点实验室(湖南师范大学),长沙410081

出　　处：《有机化学》2012年第11期2177-2180,共4页Chinese Journal of Organic Chemistry

摘　　要：在氧化银和碘化钾存在下,磺酰氯与肟室温反应合成一系列O-磺酰基肟.芳香醛肟和酮肟作为底物,产率56%～87%.不过,对硝基苯甲醛肟、脂肪醛肟及α,β-不饱和醛肟作为该反应底物时,没有获得目标产物.A series of O-sulfonyl oxime derivatives have been synthesized by the reaction of oximes with sulfonyl chlorides in the presence of silver oxide and potassium iodide. In the case of aromatic aldoximes and ketoximes, desired products were obtained in 56%-87% yields. But then no desired products were obtained whenp-nitrobenzaldoxime, aliphatic aldoximes and α,β-unsaturated aldoximes were employed as substrates in the process.

关 键 词：O-磺酰基肟 合成 肟 磺酰氯 氧化银 

分 类 号：O621.25[理学—有机化学]