生长激素释放肽及其生物学效应  

Recent Advances in Studies on Ghrelin and its Biological Functions

作　　者：来景辉[1] 范红结[2] 

机构地区：[1]宿州职业技术学院动物科学系,安徽宿州234101 [2]南京农业大学动物医学院,江苏南京210095

出　　处：《中国畜牧兽医》2012年第11期66-69,共4页China Animal Husbandry & Veterinary Medicine

基　　金：安徽省教育厅自然科学基金项目(KJ2008B060);安徽省宿州市科技攻关项目(20107201)

摘　　要：生长激素释放肽(Ghrelin)是一种在动物体内广泛存在的生长激素促分泌素受体(GHSR)的内源性配体,Ghrelin与位于下丘脑的GHSR结合后,具有促进生长激素释放、增加食欲、调节消化系统功能及能量代谢等作用。文章就Ghrelin的结构、分布、生物学效应及在畜牧业上的应用前景等方面进行综述,以期促进Ghrelin的进一步深入研究。Ghrelin,a peptide lying widely in animal bodies,is the endogenous ligand for the growth hormone secretagogue receptor（GHSR）.Ghrelin,after binding with GHSR in the hypothalamus and pituitary,not only promotes the GH releasing and increases appetite,but also adjusts the functions of digestive system and energy metabolism.This article mainly reviewed the recent developments on structure,distribution and biological effects of ghrelin as well as its potential applications in animal husbandry,which maybe promotes the further research of ghrelin.

关 键 词：GHRELIN 生长激素促分泌素 生物学效应 展望 

分 类 号：S852.2[农业科学—基础兽医学]