原发性干燥综合征59例皮肤黏膜表现分析  

The clinical analysis of 59 cases of mucocutaneous manifestations in primary Sjgren's syndrome

作　　者：王心声[1] 乔娜 付萍[3] 

机构地区：[1]周口市疾病预防控制中心专科病医院皮肤科,河南周口466000 [2]曲靖市第一人民医院皮肤科,云南曲靖655000 [3]昆明医学院附二院皮肤科,云南昆明650101

出　　处：《临床皮肤科杂志》2012年第12期716-718,共3页Journal of Clinical Dermatology

摘　　要：目的:了解原发性干燥综合征(pSS)患者皮肤黏膜表现,提高诊疗水平。方法:对59例pSS患者的临床资料进行回顾性分析。结果:59例pSS患者中,21例有皮肤黏膜表现,发生率为35.6%,其中表现为紫癜、瘀斑8例(38.1%),口腔溃疡4例(19.0%),皮肤干燥3例(14.3%),下肢红斑结节4例(19.0%),雷诺现象2例(9.5%)。结论:pSS的皮肤黏膜表现并不少见,可能使患者直接到皮肤科就诊,所以皮肤科医生应了解pSS的相关知识并予以重视,这有助于pSS早期诊断,避免误诊和漏诊。Objective： To delineate the mucocutaneous manifestations of primary Sjtigren＇s syndrome （pSS） and improve its the diagnosis and treatment. Methods： The clinical data on 59 patients with pSS were analyzed retrospectively. Results： Among the 59 patients, twenty-one （36.6%） were found to have mucocutaneous manifestations including purpura and peteehiae in 8 cases （38.1%） , oral ulcers in 4 cases （19.0%）, dry skin in 3 patients （14.3%）, erythemas and nodules on lower extremities in 4 cas- es （19.0%）, Raynaud＇s phenomenon in 2 cases （9.5%）. Conclusion： Mucocutaneous manifestations in pSS are not rare. Patients could visit dermatology clinics. Dermatologists should pay attention to and have the relevant knowledge of pSS, which could help early diagnosis and avoid misdiagnosis and missed diagnosis of pSS.

关 键 词：原发性干燥综合征 皮肤 黏膜 

分 类 号：R442.8[医药卫生—诊断学]