睾丸或附睾精子ICSI治疗无精子症  

Intracytoplasmic sperm injection for azoospermia by using epididymal or testicular sperm

作　　者：王丽[1] 陈家仙[1] 胡雪梅[1] 杨智敏[1] 

机构地区：[1]遵义医学院附属医院生殖中心,贵州遵义563000

出　　处：《遵义医学院学报》2012年第1期66-67,74,共3页Journal of Zunyi Medical University

摘　　要：目的比较睾丸和附睾精子ICSI治疗无精子症的临床效果。方法分别用睾丸或附睾来源的精子进行ICSI,对其受精率、优质胚胎率、胚胎种植率和临床妊娠率等指标进行评价。结果睾丸精子的受精率明显低于附睾精子的受精率(P<0.001),两者的优质胚胎率、胚胎种植率和临床妊娠率差异无显著性(P>0.05)。结论附睾精子较睾丸精子有更强的受精能力,但不影响治疗结局。Objective To compare the clinical results of intracytoplasmic sperm injection（ICSI） for azoospermia by using epididymal or testicular sperm.Methods The ICSI was performed using the sperm from epididymis or testis,respectively.The fertilization rate,the high quality embryo rate,the embryo implantation rate and the clinical pregnancy rate were evaluated.Results The fertilization rate from testicular sperm was obviously lower than that from epididymal sperm（P0.001）.However,there was no significant difference for the high quality embryo rate,the embryo implantation rate and the clinical pregnancy rate between the use of epididymal and testicular sperm（P0.05）.Conclusion The fertilization ability of epididymal sperm is better than that of testicular sperm,which couldn＇t change the treatment outcome.

关 键 词：无精子症 精子 卵胞浆内单精子注射 手术取精 

分 类 号：R698[医药卫生—泌尿科学]