2009～2011年1281株铜绿假单胞菌的耐药性分析  

Drug resistance analysis of 1281 strains of Pseudomonas aeruginosa from 2009 to 2011

作　　者：王玲玲[1] 李智伟[1] 韩艳[1] 

机构地区：[1]新疆维吾尔自治区人民医院检验科,新疆乌鲁木齐830001

出　　处：《中国美容医学》2012年第10X期49-50,共2页Chinese Journal of Aesthetic Medicine

基　　金：新疆维吾尔自治区人民医院科研资助项目(20110104)

摘　　要：目的:了解我院铜绿假单胞菌的耐药情况,为临床诊断疾病与合理使用抗菌药物提供科学依据。方法:回顾性分析我院2009～2011年来临床各类送检标本中铜绿假单胞菌的耐药性状况。结果:2009～2011年共分离出的1281株铜绿假单胞菌,各类标本中以痰的检出率最高,占61.9%。铜绿假单胞菌对头孢哌酮/舒巴坦的耐药率最低(9.6%)其次是阿米卡星(10.6%)、哌拉西林/他唑巴坦(11.5%)、头孢吡肟(14.6%)、左旋氧氟沙星(15.2%)、头孢他啶(16.7%)、环丙沙星(17.4%),对其他抗菌药物均有不同程度的耐药。结论:检出铜绿假单胞菌菌株有逐年增高趋势,应规范临床用药并加强实验室监测。Objective To investigate the antibiotic resistance of Pseu domonas aeruginosa （PA）,provide a scientific basis clinical diagnosis and the rational use of antimicrobial drugs. Method Retrospective analysis of PA resistance status of all kinds of censorship in our hospital from 2009 to 2011. Results 1281 strains of PA were isolated during 2009-2011,most of PA strains were isolated from sputa and the detection rate was 61.9%,the lowest resistance rate to cefoperazone/sulbactam （9.6%）,Amikacin （10.6%）, piperacillin/tazobactam （11.5% ）,cefepime （ 14.6% ）,levofioxacin （15.2%）,ceftazidime （16.7% ）,ciprofloxacin （17.4% ）,and PA have different levels of resistance toother antimicrobial. Conclusions The detection rate of PA is increasing yearly,and we should standardize the clinical use of drugs and strengthen laboratory monitoring.

关 键 词：铜绿假单胞菌 抗菌药物 耐药性 实验室监测 

分 类 号：R446.5[医药卫生—诊断学]