系统遗传学与生物技术-细胞分子生物系统的分析与合成  

Systems Genetics and Biotechnology-Analysis and Synthesis of Cell Molecular Biosystems

作　　者：曾杰(邦哲) 

机构地区：[1]邦哲系统生物工程研究所有限公司,常州213022

出　　处：《生物技术通报》2012年第10期47-51,共5页Biotechnology Bulletin

摘　　要：生物系统的科学与工程是整合系统论、实验、计算和工程方法的交叉学科研究与应用。系统生物学、系统医学,建立在系统科学和数学模型基础上,采用分子、组学生物技术和计算、生物信息技术,以及基因合成与转基因生物技术等研究生物系统原理和规律。系统遗传学与系统生物技术是研究天然与人工生物系统的基因系统与蛋白质系统构成细胞的软件信息与硬件运行系统的机理与方法。合成生物学、系统生物工程也是建立在系统科学和数学模型基础上,应用于生物系统原理设计虚拟计算机信息软件和仿生人工机器硬件、人造工程生物体和基因信息系统等。To investigate natural and artificial biosystems,systems biology which included systems genetics and systems medical study of diseases,systems biological engineering worked as synthetic biology and systems biotechnology,were established on the theoretical fundamentals of evolution,systems and structure theories.The science and engineering of biosystems are disciplines by integrative methodology of computational,experimental and engineering biology.Systems dynamics of cytogenesis and bio-molecular networks is explored as the mechanism for the evolution of genomic structures and cell lineages mapping during pattern formation of organisms.For drug discovery,micro-fluidic chips are useful for the functional analysis,identification of expression genes among difference cell-types and drug treatments,and also used for the designing of artificial cells such as neurons and neuronal communication networks etc.

关 键 词：系统生物技术 模块设计 人工合成 分子生物系统 微流控芯片 

分 类 号：Q81-3[生物学—生物工程]