苯并咪唑衍生物的合成及其反应机理研究  

Study on the Synthesis and its Mechanism for Benzimidazole Derivatives

作　　者：张学成[1] 谷静池[1] 王加忠[1] 朱必学[1] 

机构地区：[1]贵州大学大环及超分子化学重点实验室,贵阳550025

出　　处：《化学通报》2012年第11期1020-1025,共6页Chemistry

基　　金：国家自然科学基金项目(21061003);贵州省国际合作重点项目(黔科合外G字[2009]700104)资助

摘　　要：以2,2'-(邻氨基苯胺基)丙烷和水杨醛为原料,经缩合、成环作用,依次得到双席夫碱化合物L1、含一个苯并咪唑基的席夫碱L2和含双苯并咪唑基的化合物L3。采用1H NMR光谱和X-射线单晶衍射技术对化合物L1～L3的组成与结构进行了表征,推测了形成苯并咪唑衍生物的反应机理。结果表明,苯并咪唑衍生物的形成是热力学控制的。文中还对系列化合物L1～L3的UV-Vis和荧光光谱进行了考察。One di-Schiff base L1 and two benzimidazole derivatives（L2 and L3） were synthesized in turn by the reaction of 2-hydroxybenzaldehyde with 2,2′-bis（2-aminophenylamino）propane.The products were characterized by 1H NMR and X-ray diffraction single crystal structure analysis.The reaction mechanism for the formation of benzimidazole derivatives was speculated.The results showed that the formation of benzimidazole derivatives is controlled by the thermodynamics.The UV-Vis and fluorescent spectra for the three compounds L1~L3 were investigated.

关 键 词：席夫碱 苯并咪唑衍生物 结构 反应机理 

分 类 号：O626.23[理学—有机化学]