羊栖菜多糖对糖尿病大鼠肺组织保护作用及其机制  

Protective Effect of Sargassum fusiforme Polysaccharide on Lung Tissue of Type 2 Diabetes Mellitus Rats and Its Mechanism

作　　者：张杰[1] 杨骄霞[2] 杨旭东[1] 韩杨[1] 

机构地区：[1]黑龙江省牡丹江医学院,黑龙江牡丹江157011 [2]黑龙江省牡丹江医学院附属红旗医院,黑龙江牡丹江157011

出　　处：《中国食物与营养》2012年第11期72-74,共3页Food and Nutrition in China

基　　金：牡丹江医学院科学研究技术项目"羊栖菜多糖治疗2型糖尿病大鼠多脏器并发症及其机制的研究"(项目编号:2011-08)

摘　　要：不同浓度羊栖菜多糖治疗2型糖尿病大鼠,12周后,以RT-PCR检测肺组织转化生长因子β1(transforming growth factorβ1,TGF-β1)的mRNA表达,并观察肺脏组织病理变化。结果表明,羊栖菜多糖对2型糖尿病大鼠肺组织具有保护作用,其机制可能与调控TGF-β1的mRNA表达有关。Type 2 diabetes （2-DM） mellitus model rats were treated with various of SFPS. After 12 weeks, the expressions of TGF-β1 mRNA in lung tissue were detected by RT-PCR and the lung tissue were determined. Results showed SFPS could ease the injury in lung tis- sue of type 2 diabetes mellitus model rats. Its mechanism might be associated with regulating the expressions of TGF-β1 mRNA.

关 键 词：2型糖尿病 羊栖菜多糖 Β1转化生长因子 

分 类 号：R285.5[医药卫生—中药学]