济南市职工慢性肾脏病患病情况及危险因素  

Prevalence and risk factors of chronic kidney disease in the adult staff receiving physical examination from Jinan

作　　者：王坤元[1] 赵文红[1] 陈宝海[1] 朱晓辉[1] 杨剑辉[1] 

机构地区：[1]济南山东省医学科学院解放军第456医院肾内科中心,山东250031

出　　处：《国际泌尿系统杂志》2012年第6期750-755,共6页International Journal of Urology and Nephrology

摘　　要：目的调查济南市职工慢性肾脏病（CKD）的患病情况及危险因素。方法回顾性分析2007年2月～2011年5月在本院体检中心进行首次体检的成人的体检资料，分析其CKD的患病率及危险因素。结果在资料完整的10016例体检者中，血尿患病率为4．20％（95％CI为3．81％～4．59％），蛋白尿患病率为0．70％（95％CI为0．54％～0．86％），肾功能下降率为2．09％（95％CI为1．81％～2．37％），CKD患病率为6．37％（95％CI为5．89％～6．85％）。经二分类非条件Logistic回归分析，女性是血尿发生的独立危险因素。高血压、糖尿病是蛋白尿发生的独立危险因素。性别、年龄和肥胖是肾功能下降的独立危险因素。性别、年龄、肾囊肿和糖尿病是CKD的独立危险因素（P≤O．05）。结论性别、年龄、肾囊肿和糖尿病是CKD的独立危险因素，对于CKD，应加强在高危人群中的筛查，做到早发现、早干预，延缓CKD的进展，防止ESRD和CVD的发生，减轻社会及家庭的负担。Objectives To investigate the prevalence and risk factors of chronic kidney disease （CKD） in the adult staff receiving physical examination in Jinan. Methods A retrospective analysis on the first examination data of the healthy adult, analyzing the prevalence of CKD and its risk factors, from February 2007 to May 2011. Resuits In the total 10016 healthy persons, the prevalence of hematuresis was 4.20% （95 % C1：3.81% - 4.59% ）, the Prevalence of proteinuria was 0.70% （95 % C1：0.54% - 0.86% ）, reduced eGFR was 2.09% （95 % CI ： 1.81% - 2.37% ） , the prevalence of CKD was 6.37 % （95 % CI：5.89% - 6.85 % ）. After the two categories of non - con- ditional Logistic regression analysis,female is independently risk factor for hematuria. Hypertension and diabetes are risk factors for albuminuria. Gender, age and obesity are independently associated with reduced eGFR. Gender, age, renal cysts and diabetes are independently risk factors for CKD （ P ≤ O. 05）. Conclusions Gender, age, renal cysts and diabetes are independently associated with CKD. The high - risk groups of CKD should be strengthened in the screening, so early detection and intervention could help to delay the progress of CKD and prevent the occurrence of ESRD and CVD.

关 键 词：肾疾病 危险因素 山东 

分 类 号：R692[医药卫生—泌尿科学]