我院2006-2011年鲍曼不动杆菌临床分布及耐药性分析  

Clinical Distribution and Drug Resistance of Acinetobacter baumannii in Our Hospital during 2006-2011

作　　者：熊丽蓉[1] 刘耀[1] 谢林利[1] 吕军[1] 唐敏[1] 

机构地区：[1]第三军医大学第一附属医院国家药物临床试验机构,重庆400038

出　　处：《中国药房》2012年第46期4369-4370,共2页China Pharmacy

摘　　要：目的:了解我院6年来鲍曼不动杆菌的临床分布和耐药情况,以指导临床合理用药。方法:回顾性分析我院2006-2011年分离的2225株鲍曼不动杆菌临床分布及耐药情况。结果:分离前3位的科室依次为脑外科(17.0%)、重症监护室(14.0%)、呼吸科(13.3%);痰标本中检出率最高,为76.4%;鲍曼不动杆菌对碳青酶烯类耐药率较低,对其他常用抗菌药物耐药率较高。结论:我院鲍曼不动杆菌耐药情况十分严重,临床应重视合理应用抗菌药物,以减少耐药菌株的产生。OBJECTIVE： To approach the clinical distribution and drug resistance of Acinetobacter baumannii （ABA） in our hospital in 6 years, and to guide rational drug use in the clinic. METHODS： A total of 2 225 strains of isolated ABA in our hospital during 2006-2011 were analyzed retrospectively in terms of clinical distribution and drug resistance. RESULTS： Top 3 departments were department of cerebral surgery （17.0%）, ICU （14.0%）, department of respiration （13.3%）; among specimens from which ABA was isolated, sputum accounted for 76.4%; the drug resistance of ABA was serious, and among them, ABA was less resistant to carbopenems. CONCLUSION： The drug resistance of ABA is serious in our hospital. Great importance should be attached to rational use of antimicrobial agents to decrease the generation of drug-resistant bacterial strains.

关 键 词：鲍曼不动杆菌 耐药性 抗菌药物 

分 类 号：R969.3[医药卫生—药理学] R378.2[医药卫生—药学]