假紫罗兰酮环化、重排制备高纯度β-紫罗兰酮的研究  

Preparing of High Levels of Pure β-ionone from Pseudoionone via Cyclization and Rearrangement

作　　者：吴美玲[1] 曹瑞伟[2] 陈朝辉[2] 邵戴妮[1] 夏燕华[3] 邬希敏[3] 

机构地区：[1]绍兴文理学院化学化工学院,浙江绍兴312000 [2]浙江医药股份有限公司新昌制药厂,浙江新昌312500 [3]浙江医药股份有限公司维生素厂,浙江绍兴312000

出　　处：《广东化工》2012年第15期98-98,105,共2页Guangdong Chemical Industry

基　　金：绍兴文理学院大学生科研基金资助项目

摘　　要：将假紫罗兰酮环化得到α、β、γ三种紫罗兰酮的混合物,再用十二羰基铁作催化剂,使混合物重排为高纯度的β-紫罗兰酮。研究表明:环化反应收率高,催化剂可套用;重排反应β-紫罗兰酮含量大于97%,对探索高含量、低污染的β-紫罗兰酮工业合成路线具有重要指导作用。A mixture composed of α,β, γ-ionones can be prepared from pseudoionone via cyclization, which can be further converted to high levels of pure β-ionone via rearrangement using Fe3（CO）12 as the catalyst. The new β-ionone synthesis route proposed has the following advantages, such as high yield of the cyclization reaction, recovery and reuse of the catalyst Fe3（CO）12, and high levels of pure product β-ionone（〉97 %）, which is of great importance to explore a route for the synthesis of β-ionone in high purity and friendly environment.

关 键 词：Β-紫罗兰酮 环化 羰基铁 重排 

分 类 号：TQ[化学工程]