通窍救心滴丸抗心肌缺血、镇痛作用实验研究  

The effect of Tongqiaojiuxin Dropping Pills on anti-myocardial ischemia and analgesia

作　　者：柳璐[1] 黄萍[1] 翟小玲 邝兆进[1] 吴清和[1] 花汝凤 

机构地区：[1]广州中医药大学,广州510006 [2]广州星群(药业)股份有限公司,广州510288

出　　处：《西北药学杂志》2012年第6期555-557,共3页Northwest Pharmaceutical Journal

摘　　要：目的研究通窍救心滴丸的抗心肌缺血及镇痛作用。方法应用不同剂量的通窍救心滴丸灌胃给予小鼠,抗心肌缺血实验采用异丙肾上腺素致小鼠心肌缺血模型;镇痛实验采用扭体法、甲醛法。结果通窍救心滴丸对醋酸和甲醛所诱发的小鼠疼痛有明显的抑制作用;通窍救心滴丸可显著延长心肌缺血小鼠耐缺氧存活时间。结论通窍救心滴丸具有明显的抗心肌缺血及镇痛作用。Objective To investigate the anti-myocardial ischemia and analgesic effect of Tongqiaojiuxin Dropping Pills.Methods Different doses of Tongqiaojiuxin Dropping Pills were orally given to mice,using myocardial ischemia model writhing formaldehyde-induced pain in mice to observe the analgesic and anti-stress effect of Tongqiaojiuxin Dropping Pills.Results The Tongqiaojiuxin Dropping Pills can inhibit the pain induced by chemical stimulus and extend the survival time of mice.Conclusion The Tongqiaojiuxin Dropping Pills have anti-myocardial ischemia and analgesia effect.

关 键 词：通窍救心滴丸 心肌缺血 镇痛 

分 类 号：R965[医药卫生—药理学]