老年糖尿病合并肺部感染患者的病原菌及药敏分析  

Pathogen and drug sensitivity analysis of elderly diabetes mellitus patients complicated with pulmonary infection

作　　者：黄静[1] 陈艳云[1] 章保新[1] 郑大军[1] 李惠[1] 周宁[1] 许波[1] 姜远柏 胡量[1] 

机构地区：[1]武警湖南总队医院,长沙410006

出　　处：《按摩与康复医学》2012年第32期149-150,共2页Chinese Manipulation and Rehabilitation Medicine

摘　　要：目的：探讨老年糖尿病合并肺部感染患者的痛原菌分布特点和药敏试验情况，以便为临床用药提供依据。方法：取152例老年糖尿病合并肺部感染患者痰标本，培养、分离病原菌。结果：152例患者检出106株病原菌，其中苹兰阴性菌占37．74％，多为大肠埃希菌、肺炎克雷伯菌杆菌，对亚胺培南、喹诺酮类抗生素敏感；革兰阳性茼占30．19％，多为表皮葡萄球菌和金黄色葡萄球菌，对万古霉素敏感；真菌感染占32．07％，多为白假丝酵母菌，对两性霉素B、氟康唑、5-氟胞嘧啶敏感。结论：老年糖尿病患者易罹患肺部感染、混合感染现象明显厦病原茼耐药性增强，其治疗在严格控制血糖基础上，根据病原菌的特点选择敏感有效的抗生素治疗，有利于病情控靠6，对提高糖尿病患者的生活质量，降低病死率有着极其重要作用。Objective：To evaluate the pathogen distribution of diabetes mellitus complicated with pulmonary infection in the elderly patients and its drug sensitivity test, in order to provide the basis for the clinical medication. Methods： We extracted the sputum samples from 152 elderly diabetes mellitus patients complicated with pulmonary infection, and cultured, separated the pathogenic bacteria. Result： 106 strains of pathogenic bacteria were detected in 152 patients, in which the gram--negative bacilli accounted for 37.74%, including escherichia coli and klebsieUa pneumoniae, sensitive to imipenem and quinolones; The gram--positive bacilli accounted for 30. 19%, including staphylococcus epidermidis and staphylococcus aureus, sensitive to vancomyein;The fungal infection accounted for for 32.07%, including candida albicans, sensitive to amphotericin B, fluconazole and 5-- flucytosine. Conclusion： Obviously the elderly diabetic mellitus patients are susceptible to pulmonary infection and mixed infection, with drug resist- ance enhanced. In order to improve the life quality of diabetes mellitus patients, and decrease the mortality rate, it is extremely important to select sensitive and effective antibiotic therapy according to the characteristics of pathogenic bacteria, in the basis of strict glyeemic control.

关 键 词：糖尿病 肺部感染 病原菌 药敏试验 

分 类 号：R4[医药卫生—临床医学]