探析β-内酰胺酶抑制剂抗生素在临床上的应用  

Analysis of β-Lactamase Inhibitors Antibiotics Has Been Meeting in the Clinical Application

作　　者：张素红[1] 唐亚娟[1] 

机构地区：[1]华北电网有限公司北京电力医院,100073

出　　处：《首都医药》2012年第22期36-37,共2页Capital Medicine

摘　　要：目的探析β-内酰胺酶抑制剂抗生素在临床上的应用情况。方法通过分析β-内酰胺酶抑制剂抗生素的剂型,阐述其在临床上的应用情况。结果与结论β-内酰胺酶抑制剂对各种革兰阳性菌、革兰阴性菌、厌氧菌等所产生的β-内酰胺酶均有广泛的抑制作用,临床研究确认其与β-内酰胺类抗生素的复合制剂,用于呼吸系统、腹腔、皮肤和软组织等感染的经验治疗有效,用于中性粒细胞减少的发热、院内感染也有效。β-内酰胺类抗生素/β-内酰胺酶抑制剂复合制剂治疗混合感染疗效突出。Objective To explore the -lactam inhibitors in clinical application of antibiotics.Methods through the analysis of β-lactamase inhibitors antibiotic dosage forms,expounds its application in clinical situations.Results and Conclusion -lactamase inhibitors on various gram- positive,Gram-negative bacteria,anaerobic bacteria caused by β-lactamases were widespread inhibition,clinical studie.s to confirm its and β-lactam antibiotics compound,used for respiratory,intraperi toneal,skin and soft tissue.Experience of treatment for infection effectively,neutropenic fever,nosocomial infection effectively.Lactam antibiotics/β-lactamase inhibitor compound preparations in the treatment of mixed infections are notable curative effective for multiple drug resistant bacteria.

关 键 词：Β-内酰胺抗生素 酶抑制剂 复方制剂 

分 类 号：R969.3[医药卫生—药理学]