建立人胚胎干细胞系的研究进展  

Progress in the establishment of human embryonic stem cell lines

作　　者：李牧[1] 葛伟文[2] 

机构地区：[1]中国医学科学院血液学研究所实验血液学国家重点实验室,天津300020 [2]中国人民解放军军事医学科学院卫生学环境医学研究所,天津300050

出　　处：《中国病理生理杂志》2000年第3期283-285,共3页Chinese Journal of Pathophysiology

摘　　要：Embryonic stem(ES) cells are derived from totipotent cells of the early mammalian embryo and are capable of unlimited, undifferentiated proliferation in vitro. The establishment of mouse ES cell lines demonstrated the unmatchable convenience for the study of mouse embryonic development and the particular gene regulation and function. It has been long expected to construct such cell line for human. Here we summarized the development in the construction of human ES cell line, its potential utilization in various fields and the possible ethical dilemmas it brought with were also discussed.Embryonic stem(ES) cells are derived from totipotent cells of the early mammalian embryo and are capable of unlimited, undifferentiated proliferation in vitro. The establishment of mouse ES cell lines demonstrated the unmatchable convenience for the study of mouse embryonic development and the particular gene regulation and function. It has been long expected to construct such cell line for human. Here we summarized the development in the construction of human ES cell line, its potential utilization in various fields and the possible ethical dilemmas it brought with were also discussed.

关 键 词：胚胎 干细胞系 ES细胞 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]