镉对接触工人精浆果糖和转铁蛋白含量影响的研究  

Effects of Cadmium on Fructose and Transfer in Seminal Plasma From Occupationally Exposed Workers

作　　者：杨建明[1] 陈琼宇[2] 曾祥斌[1] 周袁芬[1] 金泰异 蒋学之[1] 

机构地区：[1]上海医科大学劳动卫生教研室,200032 [2]河南医科大学劳动卫生教研室

出　　处：《中国公共卫生》2000年第4期299-300,共2页Chinese Journal of Public Health

摘　　要：为探讨镉对附性腺和睾丸细胞的影响 ,采用WHO推荐的方法 ,测定镉接触工人精浆果糖和精浆转铁蛋白 ,结果 ,接触组的果糖和转铁蛋白含量均显著低于对照组 (P <0 0 5 ,P <0 0 1) ,但不同血镉浓度组间的果糖和转铁蛋白含量无明显差异。随着精浆镉浓度的升高 ,精浆果糖含量有下降趋势 (P >0 0 5 ) ,而精浆转铁蛋白含量则显著降低 (P <0 0 5 )。精浆转铁蛋白含量随着接镉工龄的延长显著降低 (P <0 0 1) ,而精浆果糖含量各工龄组间无明显差异。相关分析表明 ,精浆果糖、转铁蛋白含量与精子畸形率呈显著负相关。To study the effects of cadmium on frucose and transferrin in seminalplasma from occupationally exposed workers, the general conditions of workers were investigated with the questionnaire. The determination of frucose was carried out using the methods that WHO recommended, and transferyin was assayed by using kit.The results showed that the amount of fructose and transferrin was significantly lower in the exposed group than that in the control group (P<0.05, P<0.01), but no significant difference was found in the content of fructose and transferrin anlong different blood cadmium groups. There was a decreasing trend of the concentrations of fructose and transferrin as the increase of seminal plasma cadmium concentration.The content of transferrin in seminal plasma was reduced significantly by prolonged cadmium exposure period (P<0.01), but the content of ructose among different cadmium exposure period showed no significant difference. Comelation analysis indicated that a negatively conelative relationship between the fmctose, transferrin in the seminal plasma and the rate of malformation sperm (P<0.05).These findings suggested that the secretive functions of the testicular cell can be affected by occupational cadmium exposure.

关 键 词：镉 附性腺 果糖 转铁蛋白 精子畸形 

分 类 号：R135.1[医药卫生—劳动卫生] R995[医药卫生—公共卫生与预防医学]