桥本病并发甲状腺癌的临床分析  

Clinical research of Hashimoto′s disease with thyroid carcinoma

作　　者：徐少明[1] 王平[1] 虞志刚[1] 

机构地区：[1]浙江大学医学院附属第二医院外科,杭州市310009

出　　处：《中华医学杂志》2000年第4期278-279,共2页National Medical Journal of China

摘　　要：目的　探讨和分析桥本病 (HD)并发甲状腺癌 (TC)发病情况及诊治经验。方法　对1976年 1月～ 1999年 4月 15 0例HD病人中同时并发TC的 15例予手术治疗 ,还作病理学检查。并对2种疾病的并发率、发病机理、诊断和治疗经验进行分析。结果　HD与TC并发率为 10 % (15 / 15 0 ) ,术前确诊率 46 .7%。对 15例TC病人随访 3个月～ 19年 ,均无TC复发 ,效果满意。结论　HD与TC可能有共同的发病机理 ,即免疫缺陷和内分泌功能失调。临床上应术前常规测血甲状腺球蛋白抗体、甲状腺微粒体抗体、细针穿刺细胞学检查及术中作冰冻切片 ,利于术前和术中确诊及正确选择手术方法。Objective To study the relation diagnosis and treatment of Hashimoto's disease (HD) with thyroid carcinoma (TC). Methods The relation diagnosis and surgical treatment of 150 cases of HD including 15 cases of TC were analyzed. Results The coexistent rate of HD with TC was 10%. The 15 cases were all women, with a mean age of 36.5 years, and they were surgically treated. Follow up for 4 months to 19 years showed that the 15 cases were alive without recurrence. Conclusion Surgical treatment is indicated for patients with HD associated with TC. The essential factors for diagnosis and rational treatment are a detailed understanding of clinical feature, routine examination of serum antibodies, B ultrasonic examination and selective FNAC.

关 键 词：甲状腺炎 桥本病 并发症 甲状腺癌 临床分析 

分 类 号：R581.1[医药卫生—内分泌]