2型糖尿病患者低血糖事件发生率及费用研究  

Incidence and cost of hypoglycemia episode in patients with type 2 diabetes mellitus(T2DM)

作　　者：郑亚明[1] 吴晶[1] 谢琨[1] 

机构地区：[1]天津大学药物科学与技术学院,天津300072

出　　处：《中国农村卫生事业管理》2012年第11期1195-1198,共4页Chinese Rural Health Service Administration

摘　　要：目的:了解2型糖尿病患者低血糖事件发生率及费用情况。方法:通过对北京、天津共509名2型糖尿病患者进行问卷调查,了解2型糖尿病患者轻微、中度和严重低血糖的发生率及低血糖事件预防及治疗费用。结果:509名患者过去一年的低血糖发生率为54.03%,最近一周79人发生轻微低血糖事件146次,最近一月37人发生中度低血糖事件54次,最近一年6人发生严重低血糖事件6次。空腹血糖控制良好患者的轻微低血糖事件发生率较高,口服降糖药联合胰岛素的患者过去一年中低血糖发生率较高。轻微低血糖事件未发生医疗成本,中度低血糖事件费用为1 513.00元/次,严重低血糖费用为5 560.76元/次。结论:低血糖是2型糖尿病患者降糖治疗过程中常见的急性不良反应且发生率较高,对患者及其家庭均会带来的较大的负担。Objective To know the incidence and cost of hypoglycemia episode in patients with type 2 diabetes melli- tus （T2DM）. Methods A face--to--face interview was performed in 2 hospitals in Beijing and Tianjin with a well de- signed questionnaire in 2011. The incidence of mild, moderate and severe hypoglycemia as well as the daily preventive cost and management cost per event were investigated in this study. Results The overall incidence of the study popula- tion was 54.04% within 1 year. A total 146 mild hypoglycemia episodes were reported in 79 patients within 1 week. A total 54 moderate hypoglycemia episodes were reported in 37 patients within 1 month. A total of 6 severe hypoglycemia episodes were reported in 6 patients within 1 year. The well controlled fasting blood glucose（FBG）group had the most mild hypoglycemia episodes and the group with treatment of oral hypoglycemic agents combined with insulin had the highest hypoglycemia incidence. The mean costs for mild, moderate and severe hypoglycemia were 0,1513.00 and 5560. 76 Yuan per event separately. Conclusion Hypoglycemia, with a high incidence,is a common acute side--effect in anti- hyperglycemic treatment of T2DM patients,which is associated with considerable burden to patients and their family.

关 键 词：糖尿病 2型 低血糖 发生率 费用 

分 类 号：R587.1[医药卫生—内分泌]