冠心病患者血脂及血浆同型半胱氨酸的临床意义  

Clinical Significance of Plasma Lipid and Homocysteine in Patients with Coronary Disease

作　　者：王广兴[1] 孙华保[1] 李泽林[1] 

机构地区：[1]广东省湛江中心人民医院心内科,524037

出　　处：《岭南急诊医学杂志》2012年第5期339-340,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨血脂及血浆同型半胱氨酸(Hcy)在冠心病发生过程中的临床意义。方法:比较冠心病组110例和正常对照组78例的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、Hcy、叶酸及维生素B_(12)水平。结果:冠心病组的TC、LDL-C和Hcy水平较对照组高,叶酸及维生素B_(12)水平低,差异均有统计学意义(P<0.05);多因素Logistic回归分析显示与冠心病有关的因素是LDL-C和Hcy。结论:高LDLC和高Hcy水平均为冠心病发病相关的独立危险因素,对冠心病的诊断有一定的临床价值。Objective ：To explore the clinical significance of plasma lipid and Hcy in patients with coronary disease. Methods： TC, TG, LDL-C, HDL-C, Hcy, folic acid and vitamin B12 level were compared between the coronary disease group （n=110） and control group（n=78）. Results： Compared with the control group, the TC, LDL- C and Hcy level were higher, and folic acid and vitamin B12 level were lower with significant differences, P〈0.05. Multivariate logistic regression analyses showed that LDL-C and Hcy were significantly associated with coronary disease. Conclusion： LDL-C and Hcy are the independent risk factors of coronary disease and having diagnostic value for coronary disease.

关 键 词：冠心病 血脂 同型半胱氨酸 

分 类 号：R541.4[医药卫生—心血管疾病]