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作 者:王煜蕙[1] 戚菲[1] 项瑛[1] 冯琦[1] 杜长伟[1]
出 处:《中国疗养医学》2012年第11期963-964,共2页Chinese Journal of Convalescent Medicine
基 金:空军科技计划项目(BKJ10R014)
摘 要:目的采用脑电超慢波涨落分析仪在无创条件下观察飞行事故后飞行人员脑神经递质活动的情况。方法对事故组44名飞行人员和对照组47名普通飞行人员用脑电超慢涨落分析技术提取在清醒状态下脑神经递质系统的信息,分析飞行事故后脑神经递质的活动情况,并且用创伤后应激障碍自评量表(PTSD-SS)评估其临床症状。结果①两组飞行人员比较,γ-氨基丁酸(GABA)神经递质活动变化差异有高度统计学意义(t=6.901,P<0.01);②反复重现体验与GABA呈负相关(r=-0.780,P<0.01),与多巴胺(DA)呈正相关(r=0.451,P<0.01),差异有高度统计学意义,谷氨酸(Glu)活动与回避症状负相关,差异有统计学意义(r=-0.278,P<0.05);③警觉性增高与去甲肾上腺素(NE)神经递质相关(r=0.227,P<0.05),差异有统计学意义。结论飞行事故后人体脑神经递质活动发生变化,参与了应激反应症状的产生。Objective Using brain electric super slow wave fluctuation analyzer to observe in non-invasive condition the brain neurotransmitter activities of the flight personnel after flight accident.Methods 44 pilots in accident group and 47 regular flight personnel in control group were collected the information of brain nerve neurotransmitter system in waking state by electric super slow wave fluctuation brain analysis technology,and the activities of brain neurotransmitter after flight accidents were analyzed,and post-traumatic stress disorder from rating scale(PTSD-SS) was adopted to evaluate the clinical symptoms.Results ①The changes of gamma-aminobutyric(GABA) neurotransmitter activities in the two groups of flight personnel had very high statistical significance(t=6.901,P〈0.01);②To repeat experience and the gamma-aminobutyric(GABA) negative correlation(r=-0.780,P〈0.01) and dopamine(DA) was positively related(r=0.451,P〈0.01) with high statistical significance;glutamic acid(Glu) activities and evaded symptoms were negatively related with statistical significance(r=-0.278,P〈0.05);③Increased vigilance and norepinephrine(NE) neurotransmitter were related(r=0.227,P〈0.05) with statistical significance.Conclusion After flight accident,human brain nerve neurotransmitter activities will change and involve in the occurrence of stress reaction symptoms.
分 类 号:R85[医药卫生—航空、航天与航海医学]
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